摘要
目的探讨“三伏贴”贴敷结合雾化吸入治疗在小儿慢性咽炎中的应用效果。方法回顾性研究2020年4月至2022年3月浙江大学医学院附属第二医院临平院区儿科收治的慢性咽炎患儿100例,采用自然分组将其分为对照组和试验组,每组各50例。对照组患儿采用布地奈德每日2次雾化吸入,试验组患儿在对照组的基础上加用“三伏贴”贴敷。两组患儿均连续治疗6周,比较两组患儿治疗前后的咽痛症状改善情况、临床疗效、中医症候积分及免疫功能水平。结果两组患儿的咽痛症状均逐渐改善,治疗6周后,试验组患儿的咽痛症状改善比对照组更好[疼痛视觉模拟评分(visual analogue scale,VAS)评分:(1.44±0.73)分vs(2.15±0.57)分],差异有统计学意义(t=-5.421,P<0.001);试验组患儿的临床总有效率高于对照组[90.00%(45/50)vs 76.00%(38/50)],差异有统计学意义(χ^(2)=2.109,P=0.007)。试验组患儿的咽干、咽灼烧感、咽异物感及咽黏膜干燥等中医症候积分分别低于对照组,差异均有统计学意义(P<0.05);试验组患儿的CD4^(+)T淋巴细胞水平、CD4^(+)/CD8^(+)均高于对照组,CD8^(+)T淋巴细胞水平低于对照组[(588.56±245.87)cells/μl vs(470.29±294.41)cells/μl、(1.52±0.33)%vs(1.37±0.29)%、(317.56±234.68)cells/μl vs(442.26±289.10)cells/μl],差异均有统计学意义(P<0.05)。结论“三伏贴”贴敷结合布地奈德雾化吸入治疗小儿慢性咽炎,对改善患儿咽痛、提高患儿免疫功能有更显著的作用,值得临床深入探讨。
Objective To investigate the application effect of Sanfu-tie combined with atomization inhalation on chronic pharyngitis in children.Methods A retrospective study was performed on total of 100 children with chronic pharyngitis who were admitted to Department of Pediatrics,Linping District,the Second Affiliated Hospital,Zhejiang University School of Medicine from April 2020 to March 2022 were selected,and divided into control group and experimental group by using natural grouping 50 cases in each group.The children of control group was treated with budesonide atomization inhalation,twice a day,and the children of experimental group was treated with Sanfu-tie on the basis of the control group.Both groups were treated for 6 weeks,and the improvement of pharyngeal pain symptoms,clinical efficacy,traditional Chinese medicine(TCM)symptom scores and immune function levels were compared between the two groups before and after treatment.Results With the progress of treatment,the symptoms of pharyngalgia in the two groups were gradually improved,but after 6 weeks of treatment,the symptoms of pharyngalgia in the experimental group were more satisfactory than those in the control group[VAS:(1.44±0.73)vs(2.15±0.57)],the difference was statistically significant(t=5.421,P<0.001);the total clinical response rate of the experimental group was higher than that of the control group[90.00%(45/50)vs 76.00%(38/50)],the difference was statistically significant(χ^(2)=2.109,P=0.007).The scores of dry throat,burning sensation in throat,foreign body sensation in throat and dryness of throat mucosa in experimental group were lower than those in control group,the differences were statistically significant(P<0.05).The levels of CD4^(+)T lymphocytes and CD4^(+)/CD8^(+)in the experimental group were higher than those in the control group.CD8^(+)T lymphocyte level was lower than that of control group[(588.56±245.87)cells/μl vs(470.29±294.41)cells/μl,(1.52±0.33)%vs(1.37±0.29)%,(317.56±234.68)cells/μl vs(442.26±289.10)cells/μl],the di
作者
戚丹丹
李丽
徐彩霞
QI Dandan;LI Li;XU Caixia(Department of Pediatrics,Linping District,the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 311100,China)
出处
《中国现代医生》
2022年第27期92-95,101,共5页
China Modern Doctor
关键词
三伏贴
雾化吸入
小儿慢性咽炎
免疫功能
Sanfu-tie
Atomization inhalation
Chronic pharyngitis in children
Immune function
