摘要
目的 明确非紫绀型先天性心脏病儿童的心肺耐力状况。方法 收集175例4~18岁非紫绀型先天性心脏病儿童(先天性心脏病组)的相关临床资料,对儿童身高、体质量、体质量指数(body mass index,BMI)等生长发育指标及经6 min步行试验(six-minute walk test, 6MWT)评估的心肺运动耐力结果进行回顾性分析,以年龄、性别匹配的377名健康儿童作为正常对照组。结果 6MWT评估结果显示:先天性心脏病组平均步行距离(520.0 m)显著低于正常对照组(590.0 m),差异有统计学意义(P<0.001);试验前后,两组儿童心率、呼吸频率、血压、血氧饱和度等指标均在正常范围内,运动过程中儿童对运动的生理反应也均在正常范围内,无不良事件发生。先天性心脏病组生长发育指标显著落后于正常对照组,差异均有统计学意义(P身高=0.022,P体质量=0.002,PBMI=0.003)。结论 6MWT可用于非紫绀型先天性心脏病儿童心肺运动耐力评估,此型先天性心脏病的心肺运动耐力低于同龄健康儿童。
Objective To evaluate the cardiorespiratory exercise tolerance of children with acyanotic congenital heart disease(CHD). Methods Relevant clinical data of 175 children aged 4-18 years with acyanotic CHD(CHD group) were collected. The children’s height, weight, body mass index(BMI) and other growth and development indicators and the results of cardiorespiratory exercise tolerance assessed by the six-minute walk test(6MWT) were retrospectively analyzed, with 377 age-and sex-matched healthy children as the normal control group(NC group). Results The 6MWT results showed that the average walking distance(520.0m) in the CHD group was significantly shorter than that in the NC group(590.0m)(P<0.001). In both groups, the heart rate, breath frequency, blood pressure, and blood oxygen saturation were all within the normal range pre-and post-test, and the children’s physiological response to exercise was also within the normal range. No adverse events occurred. The growth and development indexes of the CHD group were significantly lower than those of the NC group(P=0.022, P=0.002, P=0.003). Conclusion The 6MWT is a reliable test which can be used as a practical tool for assessing the cardiorespiratory exercise tolerance of children with acyanotic CHD, and also this population have lower cardiorespiratory exercise tolerance than healthy children.
作者
梁菊萍
周璇
宋圆圆
于虹
范起萌
诸小青
李颖娴
孙锟
杜青
LIANG Juping;ZHOU Xuan;SONG Yuanyuan;YU Hong;FAN Qimeng;ZHU Xiaoqing;LI Yingxian;SUN Kun;DU Qing(Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;Department of Rehabilitation Medicine,Xinhua Hospital Chongming Branch,Shanghai Jiao Tong University School of Medicine,Shanghai 202150,China)
出处
《教育生物学杂志》
2022年第5期399-404,共6页
Journal of Bio-education
基金
上海市卫生健康委员会省域重点疾病诊疗能力建设项目
崇明区医学重点专科项目
上海交通大学“交大之星”计划医工交叉研究基金(YG2019ZDA23)
上海市进一步加快中医药传承创新发展三年行动计划(2021─2023)项目[ZY(2021—2023)-0201-05]。
关键词
非紫绀型
先天性心脏病
心肺运动耐力
6
min步行试验
acyanotic
congenital heart disease
cardiorespiratory exercise tolerance
six-minute walk test
