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以低血糖为首发症状的盆腔恶性孤立性纤维瘤1例

A case of pelvic malignant solitary fibrous tumor with hypoglycemia as the first symptom
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摘要 通过对患者临床资料进行分析,详细描述本院诊断的1例由盆腔恶性孤立性纤维瘤(MSFT)过度分泌胰岛素样生长因子-Ⅱ(IGF-Ⅱ)导致患者发作性低血糖伴低血钾的罕见病例。该患者低血糖发作时血清胰岛素水平明显降低,考虑为非胰岛细胞肿瘤性低血糖,CT检查结果显示盆腔存在巨大MSFT占位,经手术切除后随访1年患者未在发生低血糖及低血钾症状。国内外此类病例报道罕见,通过本例病例的报道,以期提高临床医生对此类疾病的认识。 A rare case of episodic hypoglycemia with hypokalemia caused by insulin-like growth factor(IGF)-Ⅱsecreted by a giant pelvic malignant solitary fibrous tumor(MSFT)was investigated through comprehensively reviewing her medical history and clinical records.The patient’s serum insulin level was significantly reduced during the hypoglycemia episode,which was considered to be non-islet-cell tumor hypoglycemia.CT examination results showed a huge MSFT mass in the pelvis,after surgical resection,there was no recurrence of symptoms of hypoglycemia and hypokalemia during 1 year follow-up.Reports of such cases at home and abroad are rare.Through the report of this case,we hope to improve clinicians’understanding of such diseases.
作者 王斓惠 孔磊 胡海颖 张焱 何永 韩文霞 Wang Lanhui;Kong Lei;Hu Haiying;Zhang Yan;He Yong;Han Wenxia(Shandong University of Traditional Chinese Medicine,J inan250355,China;Department of Endocrinology and Metabolism(Shandong Provincial Hospital),Jinan250021,China;Blood Transfusion Branch,The First Affiliated Hospital of Shandong First Medical University(Qianfoshan Hospital of Shandong Province),Jinan 250014,China;Outpatient Department,East Hospital of Shandong Provincial Hospital,Jinan 250021,China;School of Management,Shandong University of Traditional Chinese Medicine,Jinan 250355,China)
出处 《实用妇科内分泌电子杂志》 2022年第10期84-87,共4页 Electronic Journal of Practical Gynecological Endocrinology
基金 国家自然科学基金项目(编号81273880、30701130) 山东省卫健委(编号YXH2019ZXY002)。
关键词 盆腔恶性孤立性纤维瘤 胰岛素样生长因子Ⅱ 非胰岛细胞肿瘤性低血糖 Pelvic malignant solitary fibrous tumor Insulin-like growth factorⅡ Non-islet-cell tumor hypoglycemia
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