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胶体果胶铋联合奥美拉唑治疗慢性胃炎的效果分析 被引量:1

Analysis of the effect of colloidal bismuth pectin combined with omeprazole in the treatment of chronic gastritis
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摘要 目的分析胶体果胶铋联合奥美拉唑治疗慢性胃炎的临床效果。方法100例慢性胃炎患者,通过随机分组的方式分为实验组和对照组,各50例。对照组患者采取胶体果胶铋进行治疗,实验组患者应用胶体果胶铋联合奥美拉唑进行治疗。对比两组患者治疗效果、胃功能评分、幽门螺杆菌根除情况。结果实验组患者总有效率96%高于对照组的70%,差异具有统计学意义(P<0.05)。实验组患者接受功能、储存功能、分泌功能、消化功能、运输及排空功能评分分别为(11.6±2.4)、(13.6±2.8)、(13.7±2.6)、(10.4±2.8)、(9.1±2.2)分,均高于对照组的(9.3±1.3)、(10.8±2.0)、(9.7±1.8)、(7.5±1.7)、(7.4±1.5)分,差异具有统计学意义(P<0.05)。实验组患者幽门螺杆菌根除率82%高于对照组的60%,差异具有统计学意义(P<0.05)。结论针对慢性胃炎患者采取胶体果胶铋联合奥美拉唑治疗效果比较理想,其可明显改善胃功能,对根除幽门螺杆菌效果明显,值得临床推荐。 Objective To analyze the clinical effect of colloidal bismuth pectin combined with omeprazole in the treatment of chronic gastritis.Methods A total of 100 patients with chronic gastritis were randomly divided into experimental group and control group,with 50 cases in each group.The control group was treated with colloidal bismuth pectin,and the experimental group was treated with colloidal bismuth pectin combined with omeprazole.The therapeutic effect,gastric function score and Helicobacter pylori eradication were compared between the two groups.Results The total effective rate 96%in the experimental group was higher than 70% in the control group,and the difference was statistically significant(P<0.05).The scores of receiving function,storage function,secretion function,digestive function,transportation and emptying function in the experimental group were(11.6±2.4),(13.6±2.8),(13.7±2.6),(10.4±2.8)and(9.1±2.2)points,which were higher than(9.3±1.3),(10.8±2.0),(9.7±1.8),(7.5±1.7)and(7.4±1.5)points in the control group,and the differences were statistically significant(P<0.05).The eradication rate of Helicobacter pylori 82% in the experimental group was higher than 60% in the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with chronic gastritis,colloidal bismuth pectin combined with omeprazole has an ideal therapeutic effect.It can significantly improve gastric function and has a significant effect on eradication of Helicobacter pylori,which is worthy of clinical recommendation.
作者 李丹丹 LI Dan-dan(Department of Gastroenterology,Liaoning Health Industry Group Fukuang General Hospital,Fushun 113000,China)
出处 《中国现代药物应用》 2022年第17期125-127,共3页 Chinese Journal of Modern Drug Application
关键词 胶体果胶铋 奥美拉唑 慢性胃炎 运动疗法 Colloidal bismuth pectin Omeprazole Chronic gastritis Kinesitherapy
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