摘要
目的探讨骨质疏松性髋部骨折患者术前深静脉血栓形成(DVT)的危险因素。方法回顾性分析泉州市正骨医院2018年6月至2021年9月收治的323例骨质疏松性髋部骨折患者的一般临床资料(年龄、性别、骨折类型、骨折侧别、是否患有高血压、是否患有糖尿病、骨折至入院时间)、入院24 h内实验室检测结果(血型、抗凝血酶、纤维蛋白原、D-二聚体、血红蛋白、红细胞压积、总胆固醇、三酰甘油)及术前患肢彩色多普勒超声检查结果。根据超声检查结果将研究对象分为DVT组和非DVT组。对各相关影响因素进行单因素分析和多因素Logistic回归分析,确定术前发生DVT的独立危险因素。结果323例中41例发生DVT,其中近端血栓8例、远端血栓28例(肌间静脉血栓22例)、混合血栓5例。单因素分析显示,术前DVT组和非DVT组在骨折侧别、是否患有高血压、是否患有糖尿病、实验室检测结果等方面差异均无统计学意义(P均>0.05),而年龄、性别、骨折类型、骨折至入院时间差异均有统计学意义(P均<0.05)。多因素Logistic回归分析显示,性别(OR=6.695,95%CI:1.541~29.087,P<0.05)、骨折类型(OR=4.094,95%CI:1.929~8.688,P<0.05),骨折至入院时间(OR=4.046,95%CI:1.839~8.906,P<0.05)与术前发生DVT相关。结论女性、股骨粗隆间骨折、骨折至入院时间≥24 h是骨质疏松性髋部骨折患者术前DVT发生的独立危险因素,患者骨折后应尽早就诊,早期接受抗凝治疗并积极筛查DVT。
Objective To investigate the risk factors of preoperative deep vein thrombosis(DVT)in patients with osteoporotic hip fracture.Methods A retrospective analysis was performed on the general clinical data of 323 patients with osteoporotic hip fracture admitted to Quanzhou Osteopathic-Traumatological Hospital from June 2018 to September 2021,including age,gender,fracture type,fracture side,hypertension,diabetes,fracture to admission time,and the laboratory test results in 24 h of admission,including blood group,antithrombin,fibrinogen,D-dimer,hemoglobin,hematocrit,total cholesterol,triacylglycerol,and the results of preoperative color Doppler ultrasound examination of the affected limb.According to the results of ultrasonic examination,the subjects were divided into DVT and non-DVT group.The univariate analysis and multivariate Logistic regression analysis were performed to determine the independent risk factors for preoperative DVT.Results Among the 323 cases,41 cases developed DVT,including 8 cases of proximal thrombosis,28 cases of distal thrombosis(22 cases of intramuscular vein thrombosis)and 5 cases of mixed thrombosis.The univariate analysis showed that there was no statistically significant differences between the DVT group and the non-DVT group in preoperative fracture side,hypertension,diabetes and laboratory test results(all P>0.05),while there were statistically significant differences in age,gender,fracture type and time from fracture to admission(all P<0.05).The multivariate logistic regression analysis showed that gender(OR=6.695,95%CI:1.541-29.087,P<0.05),fracture type(OR=4.094,95%CI:1.929-8.688,P<0.05),time from fracture to admission(OR=4.046,95%CI:1.839-8.906,P<0.05)was significantly correlated with the occurrence of preoperative DVT.Conclusion Female,intertrochanteric fracture of femur and fracture to admission time≥24 h were the independent risk factors for preoperative DVT in the patients with osteoporotic hip fracture.The patients should seek medical treatment as soon as possible after fractur
作者
赖珊珊
饶华春
林夏莲
吴天然
LAI Shanshan;RAO Huachun;Lin Xialian;WU Tianran(Department of Medical Laboratory,Quanzhou Orthopedic-Traumatological Hospital,Quanzhou 362000,Fujian,China;Department of Ultrasonic Examination,Quanzhou Orthopedic-Traumatological Hospital,Quanzhou 362000,Fujian,China;Department of Lower Limb,Quanzhou Orthopedic-Traumatological Hospital,Quanzhou 362000,Fujian,China)
出处
《临床检验杂志》
CAS
2022年第8期600-603,共4页
Chinese Journal of Clinical Laboratory Science
关键词
骨质疏松
股骨粗隆间骨折
深静脉血栓形成
危险因素
骨折至入院时间
osteoporosis
intertrochanteric fracture of femur
deep vein thrombosis
risk factors
fracture to admission time
