摘要
目的研究影响进行高强度聚焦超声治疗的子宫肌瘤妇女疗效的影响因素,以期提高患者预后。方法388例子宫肌瘤患者的选取时间段为2015年3月至2018年3月,均在我院接受治疗,根据治疗后患者的子宫肌瘤消融率进行分组,其中低消融率患者为77例患者,低消融率定义为患者进行消融后病灶的直径降低率低于50%;中消融率组为132例患者,中消融率定义为患者进行消融后病灶的直径降低率在50%~75%之间;高消融率组为179例患者,高消融率定义为患者进行消融后病灶的直径降低率超过75%。上述所有患者均进行为期6个月的随访调查,查阅病案记录患者病灶相关情况,包括病灶的直径、位置以及超声时MRI信号,对上述获取的资料进行统计学分析,比较相关的影响因素。结果低消融率组子宫肌瘤大小显著低于中和高消融组,子宫肌瘤大小在>50mm以上的患者占比比较发现,高消融组占比最高,三组患者的肌瘤位置也有显著差别,低消融组患者侧壁占比最高,中消融组和高消融组患者子宫肌瘤位置位于前壁占比最高(P<0.05);低消融率组T_(1)WI增强强度和T_(2)WI信号与其他组别比较可知,低消融组均较高,中等消融率组T_(1)WI增强强度和T_(2)WI信号强度均处于中等水平,高消融率组相较于其他两组的T_(1)WI增强强度和T_(2)WI信号强度均较低(P<0.05);对上述具有统计学差异的单因素进行多因素的回归分析,结果显示,患者的子宫肌瘤直径超过50mm、子宫肌瘤病灶位置位于子宫前壁、T_(1)WI增强强度和T_(2)WI信号强度较低,均会影响患者进行高强度聚焦超声治疗的效果。结论患者的子宫肌瘤直径超过50mm、子宫肌瘤病灶位置位于子宫前壁、T_(1)WI增强强度和T_(2)WI信号强度较低,均会影响患者进行高强度聚焦超声治疗的效果,应在临床上引起重视并及时干预。
Objective To explore the factors related to the efficacy of high-intensity focused ultrasound in women with uterine fibroids,aiming to improve the therapeutic effect of women with uterine fibroids.Method 388 women with uterine fibroids who were treated in our hospital from March 2015 to March 2018 were selected as subjects.Patients were divided into low ablation rate group(Diameter reduction rate<50%,77 cases),moderate ablation rate group(Diameter reduction rate of 50%to 75%,132 cases)and high ablation rate group(Diameter reduction rate>75%,179 cases)according to uterine fibroid ablation rate.The size,location,and MRI signal strength of uterine fibroids in the three groups were compared.Followed up for 6 months,multivariate logisitic regression analysis was performed on statistically significant indicators,to explore the influencing factors of high efficacy of high-intensity focused ultrasound in women with uterine fibroids.Result The size,type,and position ratio of uterine fibroids in the moderate ablation rate group were balanced.The size of uterine fibroids in the high ablation rate group was mainly>50mm.The type of fibroids was mainly subserosal and submucosal,and the position of fibroids was mainly in the anterior wall(P<0.05).The low ablation rate group had high T_(1)WI enhancement intensity,T_(2)WI signal intensity was high,moderate ablation rate group had moderate T_(1)WI enhancement intensity,T_(2)WI signal intensity was moderate,high ablation rate group had low T_(1)WI enhancement intensity,and T_(2)WI signal intensity was low(P<0.05).Multivariate logisitic regression analysis showed that uterine fibroid size>50mm,location of anterior wall,low T_(1)WI enhancement intensity,and low T_(2)WI signal intensity were the influencing factors for high-intensity focused ultrasound in women with uterine fibroids.Conclusion The effectiveness of high intensity focused ultrasound in women with uterine fibroids depends on the size,location,T_(1)W amplification and T_(2)W signal intensity of uterine fibroids,which shou
作者
周玉珍
钱以琳
束长珍
顾红芳
卞晓艳
陈惠娴
顾晓枫
ZHOU Yu-zhen;QIAN Yi-lin;SHU Chang-zhen;GU Hong-fang;BIAN Xiao-yan;CHEN Hui-xian;GU Xiao-feng(Department of Obstetrics and Gynecology,Suzhou Hospital of Integrated Chinese and Western Medicine,Suzhou 215101,Jiangsu Province,China)
出处
《中国CT和MRI杂志》
2022年第10期112-114,共3页
Chinese Journal of CT and MRI
基金
2018年度苏州市临床重点病种诊疗技术专项项目(LCZX201827)。
关键词
子宫肌瘤
高强度聚焦
超声疗效
相关因素
Uterine Fibroids
High Intensity Focusing
Ultrasound Efficacy
Related Factors
