摘要
目的 归纳总结血培养标本病原微生物的分布特征,对比探讨血流感染患者与非血流感染患者感染指标的差异。方法 选择2020年1月—2021年10月盐城市大丰人民医院收治的140例住院患者,根据是否存在血流感染分为观察组(血流感染者)70例与对照组(非血流感染患者)70例,均进行血培养标本病原微生物检测及感染指标测定。总结患者血培养标本病原微生物的具体分布情况,对比两组患者感染指标测定结果。结果 共检出阳性病原微生物样本77株,其中革兰阳性菌共22株,其中表皮葡萄球菌、金黄色葡萄球菌占比较高;革兰阴性菌共55株,其中以大肠埃希菌、肺炎克雷伯菌占比较高。观察组患者PCT水平(6.37±0.31)ng/mL、CRP(43.59±3.28)mg/L、NEU(87.25±7.79)%显著高于对照组,差异有统计学意义(t=170.217、104.387、19.639,P<0.05)。结论 血培养标本病原微生物的检测能够有效鉴别患者病原菌分布,进而合理选择抗菌药物治疗,且通过检测感染指标可为临床诊断血流感染提供可靠数据支持。
Objective To summarize the distribution characteristics of pathogenic microorganisms in blood culture specimens, and to compare the differences in infection indicators between patients with bloodstream infection and those without bloodstream infection.Methods A total of 140 inpatients admitted to Yancheng Dafeng People’s Hospital from January 2020 to October 2021 were selected. According to the existence of bloodstream infection, 70 cases were divided into observation group(patients with bloodstream infection) and 70 cases in control group(patients without bloodstream infection). Blood culture specimens were tested for pathogenic microorganisms and infection indicators were determined. The specific distribution of pathogenic microorganisms in the blood culture specimens of the patients was summarized, and the measurement results of infection indicators of the two groups of patients were compared.Results A total of 77 strains of positive pathogenic microorganisms were detected, of which 22 strains were gram-positive, of which Staphylococcus epidermidis and Staphylococcus aureus accounted for a higher proportion. A total of 55 gram-negative strains were identified, among which Escherichia coli and Klebsiella pneumoniae accounted for a higher proportion. The levels of PCT in the observation group were(6.37±0.31) ng/mL, CRP(43.59±3.28) mg/L,and NEU(87.25±7.79)%, significantly higher than those in the control group, the difference was statistically significant(t=170.217, 104.387, 19.639, P<0.05).Conclusion The detection of pathogenic microorganisms in blood culture specimens can effectively identify the distribution of pathogenic bacteria in patients, and then reasonably choose antibiotics for treatment. The detection of infection indicators can provide reliable data support for clinical diagnosis of bloodstream infections.
作者
管飞菲
GUAN Feifei(Department of Laboratory Medicine,Dafeng People's Hospital,Yancheng,Jiangsu Province,224100 China)
出处
《系统医学》
2022年第16期32-35,共4页
Systems Medicine
关键词
血培养标本
病原微生物
分布特征
血流感染
感染指标
Blood culture specimens
Pathogenic microorganisms
Distribution characteristics
Bloodstream infection
Infection indicators
