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卵巢畸胎瘤相关抗N-甲基-D-天冬氨酸受体脑炎的临床诊治中国专家共识(2022年版) 被引量:8

Chinese expert consensus on clinical diagnosis and treatment of NMDAR receptor encephalis related to ovarian teratoma(2022 edition)
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摘要 卵巢畸胎瘤(ovarian teratomas,OT)是最常见的卵巢生殖细胞肿瘤(ovarian germ cell tumors,GCTs),抗N-甲基-D-天冬氨酸受体(N-Methyl-D-Aspartate Receptor,NMDAR)脑炎是OT罕见的并发症之一,属于自身免疫性脑炎(auto⁃immune encephalitis,AE)的一种,是OT引起的副肿瘤神经综合征(paraneoplastic neurological syndromes,PNS)的最常见类型。2007年首次发现了抗NMDAR抗体并报道了抗NM⁃DAR脑炎(NMDAR antibody encephalitis,NMDARE)与OT之间的相关性[1]。自2010年国内引入并建立抗NMDAR抗体诊断试验并报道首例NMDARE以来[2],随着AE相关自身抗体检测技术的开展,临床确诊的病例数也随之逐渐增加[3-6]。
出处 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2022年第9期900-906,共7页 Chinese Journal of Practical Gynecology and Obstetrics
基金 国家自然科学基金(81974454)。
关键词 卵巢畸胎瘤 抗N-甲基-D-天冬氨酸受体脑炎 诊断 治疗 专家共识 ovarian teratoma NMDAR receptor encephalitis diagnosis treatment expert consensus
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