摘要
宣肺止嗽合剂用于咳嗽之风邪犯肺证具有良好的临床疗效及安全性。在临床医生问卷调查和宣肺止嗽合剂研究文献系统回顾的基础上,采用国际临床医学专家共识研制方法,基于现有最佳证据,充分结合专家经验,遵循“循证为主,共识为辅,经验为鉴”的原则,国内33位中、西医临床与方法学等多学科专家共同研制该共识,旨在进一步提高临床医生对该药的认识,更好地指导其临床合理用药。共识采用国际公认的证据分级推荐标准:GRADE分级。专家共识意见的形成采用名义组法,主要考虑证据质量、疗效、安全性、经济性、患者可接受性及其他等6个方面的因素。如果证据充分则形成“推荐意见”,采用GRADE网格计票规则;如果证据不充分,则形成“共识建议”,采用多数计票规则。共识对宣肺止嗽合剂用于咳嗽之风邪犯肺证的疗效、用法用量、疗程进行了推荐或建议,并完善了安全性信息,并通过专家会议以及函审的方式,在全国范围内进行征求意见和同行评议,可为临床的合理用药提供参考。
Xuanfei Zhisou Mixture(宣肺止嗽合剂)has good clinical efficacy and safety when treating cough(wind evil invading lung syndrome).Based on questionnaire investigation of doctors and a systematic review of research literature on Xuanfei Zhisou Mixture,using international clinical practice guidelines’ developing methods,with the best available evidence and fully combining experts’ experience,and following the principle of “evidence-based,consensus-based and experience-based”,the expert consensus statement on Xuanfei Zhisou Mixture in clinical practice was developed by 33 multidisciplinary experts from the nationwide,aimed at guiding and standardizing the rational use of Xuanfei Zhisou Mixture.The expert consensus adopted internationally recognized recommendation criteria for classification of evidence:GRADE system.The formation of expert consensus adopted the nominal group technique.Six main considerations were quality of evidence,curative effect,safety,economical efficiency,patient acceptability and other factors.If there was sufficient evidence,a “recommendation” was formed,using GRADE grid voting rule.If there was no sufficient evidence,a “consensus opinion” was formed,using majority counting rule.The expert consensus focused on the indication,usage and dosage,and safety of Xuanfei Zhisou Mixture.Through experts’ meetings and correspondence,a nationwide consultation and peer review was conductedto provide guidance and reference for the rational use of Xuanfei Zhisou Mixture.
作者
张洪春
王成祥
崔红生
杨道文
高峰
中华中医药学会肺系病分会代表编制组
ZHANG Hongchun;WANG Chengxiang;CUI Hongsheng;YANG Daowen;GAO Feng;Representative Preparation Group of Lung Diseases Branch of Chinese Society of Traditional Chinese Medicine(China-Japan Friendship Hospital,Beijing 100010,China;The Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine,Beijing 100029,China;Wangjing Hospital of Chinese Academy of Traditional Chinese Medicine,Beijing 100102,China;不详)
出处
《中华中医药学刊》
CAS
北大核心
2022年第8期252-258,共7页
Chinese Archives of Traditional Chinese Medicine
关键词
宣肺止嗽合剂
咳嗽
风邪犯肺证
专家共识
Xuanfei Zhisou Mixture(宣肺止嗽合剂)
cough
wind evil invading lungsyndrome
expert consensus
