摘要
心力衰竭是心血管疾病患者死亡的主要原因,具有致残率、死亡率高的特点。为了降低心血管疾病患者的死亡率,临床根据不同心力衰竭发病机制不断研发治疗药物,而针对不同靶点治疗心力衰竭的新型药物上市,使心血管病变患者病情进展得到缓解,延长预期寿命。达格列净就是心血管疾病治疗研发新药之一,本文将对达格列净的药理作用、作用机制、治疗效果等方面进行阐述,为临床医师治疗心血管疾病提供选择。
Heart failure is the main cause of death in patients with cardiovascular disease,with high morbidity and mortality.In order to reduce the mortality of patients with cardiovascular disease,therapeutic drugs have been developed according to the pathogenesis of different types of heart failure.The listing of new drugs for heart failure with different targets on the market can alleviate the disease progress of patients with cardiovascular disease and prolonglife expectancy.Dapagliflozin is one of the new drugs developed for the treatment of cardiovascular diseases.This paper elaborates on the pharmacological effect,mechanism and therapeutic effect of dapagliflozin,so as to provide clinicians with choices in the treatment of cardiovascular diseases.
作者
张秀华
邓锐
黄才
黄光敏
ZHANG Xiuhua;DENG Rui;HUANG Cai;HUANG Guangmin(Department of Cardiology,Baise people's Hospital,Baise 533000,China)
出处
《现代诊断与治疗》
CAS
2022年第10期1452-1454,共3页
Modern Diagnosis and Treatment
关键词
达格列净
心血管疾病
心力衰竭
应用进展
Dapagliflozin
Cardiovascular disease
Heart failure
Application progress
