摘要
目的 探讨妊娠中期经阴道超声弹性成像(E-Cervix)技术对自发性早产的预测价值。方法 选取我院2018年1月至2020年12月收治的122例孕产妇患者为研究对象,根据妊娠结局将其分为早产组和足月分娩组,对其病例资料及超声检测结果(妊娠中期宫颈长度和宫颈内口组织弹性)进行回顾性分析。采用多因素Logistic回归分析妊娠女性早产的影响因素;采用受试者工作特征(ROC)分析的曲线下面积(AUC)评估妊娠中期宫颈长度、宫颈内口组织弹性值对早产的预测价值。结果 多因素Logistic分析显示,年龄>29~36岁(OR=4.191,95%CI:2.426~7.240)、有流产史(OR=4.860,95%CI:2.813~8.395)、妊娠期高血压(OR=4.740,95%CI:2.744~8.188)、妊娠期糖尿病(OR=6.315,95%CI:3.656~10.909)均为孕妇自发性早产的危险因素。孕妇妊娠中期宫颈长度越短(OR=0.601,95%CI:0.315~0.948)、宫颈内口组织弹性值越小(OR=0.673,95%CI:0.319~0.971),其早产的发生风险越高。ROC分析显示,妊娠中期宫颈长度(AUC=0.755)、宫颈内口组织弹性值(AUC=0.738)均对孕妇自发性早产具有一定的预测价值,且两个指标联合的预测价值高于单一指标(AUC=0.849)。结论 妊娠中期经阴道超声E-Cervix弹性成像技术对自发性早产具有较高的预测效能。
Objective To explore the predictive value of transvaginal ultrasound elastography(E-cervix) in the second trimester of pregnancy for spontaneous preterm birth.Methods 122 pregnant women admitted to our hospital from January 2018 to December 2020 were selected as the research objects.They were divided into premature delivery group and full-term delivery group according to the pregnancy outcome.The case data and ultrasonography results(the cervical length and the elasticity of cervical internal orifice tissue in the second trimester of pregnancy) were analyzed retrospectively.Multivariate Logistic regression was used to analyze the influencing factors of preterm delivery in pregnant women.The area under the curve(AUC) of receiver operating characteristic(ROC) analysis was used to evaluate the predictive value of cervical length in the second trimester of pregnancy and the elasticity of cervical internal orifice tissue for preterm birth.Results Multivariate Logistic analysis showed that age>29~36 years old(OR=4.191,95%CI: 2.426-7.240),history of abortion(OR=4.860,95%CI: 2.813-8.395),gestational hypertension(OR=4.740,95%CI: 2.744-8.188) and gestational diabetes mellitus(OR=6.315,95%CI: 3.656-10.909) were all risk factors for spontaneous preterm birth.In the second trimester of pregnancy, the shorter the cervical length(OR=0.601,95%CI: 0.315-0.948) and the smaller the elasticity value of cervical internal orifice tissue(OR=0.673,95%CI: 0.319-0.971),the higher the risk of premature birth.ROC analysis showed that the cervical length in the second trimester of pregnancy(AUC=0.755) and the elasticity of cervical internal orifice tissue(AUC=0.738) had certain predictive value for spontaneous preterm delivery of pregnant women, and the predictive value of the two indicators combined was higher than that of a single indicator(AUC=0.849).Conclusion The transvaginal ultrasound E-Cervix elastography in the second trimester has high predictive performance for spontaneous preterm birth.
作者
蔡蓉
崔琪
丁洁
CAI Rong;CUI Qi;DING Jie(Department of Function,Wuxi Maternal and Child Health Hospital of Nanjing Medical University,Jiangsu Wuxi 214000,China)
出处
《中国妇幼健康研究》
2022年第8期37-41,共5页
Chinese Journal of Woman and Child Health Research
基金
江苏省自然科学基金(BK20170209)。
关键词
自发性早产
妊娠中期
经阴道超声弹性成像
预测效能
spontaneous preterm birth
the second trimester
transvaginal ultrasound elastography-cervix
predictive performance
