摘要
T2DM高患病率、致残率给全球带来沉重的社会负担,需深入研究T2DM发病机制及其治疗靶点。近年来,肠道菌群与T2DM的相关性逐渐受到重视,T2DM患者肠道菌群丰度与健康人群存在明显差异,肠道菌群改变会影响肠道多种肽类激素分泌,从而影响血糖水平。T2DM患者使用具有调节肠道菌群作用的药物后,血糖水平得到控制。本文对肠道菌群与T2DM相关性的研究进展进行综述。
The high prevalence and disability rate of type 2 diabetes mellitus(T2DM)brougt a heavy social burden to the world.It is necessary to deeply study the pathogenesis and therapeutic targets of T2DM.In recent years,more and more attention was paid tothe relationship between intestinal flora and T2DM.The intestinal flora abundance was not only significantly different in T2DM patients,but the changes of it also affected intestinal polypeptide hormones,thus affected blood glucose level.The blood glucose level was controlled in T2DM patients after using drugs with the effect of regulating intestinal flora.This paper reviews the research progress of the correlation between intestinal flora and T2DM.
作者
牟荣菲
王绵
刘瑞红
陈枫
毕然然
许玉华
杨昭
MOU Rongfei;WANG Mian;LIU Ruihong(Department of Endocrinology,The Second Hospital of He Bei Medical University,Shijiazhuang,050000,China)
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2022年第8期636-640,共5页
Chinese Journal of Diabetes
关键词
糖尿病
2型
肠道菌群
相关性
Diabetes mellitus,type 2
Intestinal flora
Correlation
