摘要
目的:分析急性咽喉炎患者应用雾化吸入布地奈德混悬液的疗效。方法:选取2019年1月-2020年1月,大冶市人民医院耳鼻咽喉科治疗的84例急性咽喉炎患者,随机分为药物组和雾化组,各42例。药物组行一般药物治疗,雾化组行雾化吸入布地奈德混悬液治疗,对比两组患者临床疗效、疾病症状消退时间、治疗前后炎症因子水平及不良反应情况。结果:雾化组有效率高于药物组,差异有统计学意义(P<0.05);雾化组咳嗽、全身发热、咽喉肿痛和声音嘶哑的消退时间短于药物组,差异有统计学意义(P<0.05);治疗前,两组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平比较,差异无统计学意义(P>0.05);治疗后,雾化组TNF-α、IL-6、CRP水平均低于药物组,差异有统计学意义(P<0.05);雾化组不良反应发生率低于药物组,差异有统计学意义(P<0.05)。结论:对急性咽喉炎患者应用雾化吸入布地奈德混悬液治疗,患者的临床疗效有明显提升,在改善炎症因子水平的同时,能够快速缩短疾病相关症状的消退时间,应用雾化吸入布地奈德混悬液治疗后患者不良反应的发生情况明显降低,减轻了疾病带来的痛苦,其临床应用价值高,值得推广普及。
Objective:To analyze the efficacy of budesonide suspension atomization inhalation in patients with acute pharyngitis.Methods:From January 2019 to January 2020,84 patients with acute pharyngitis treated in the Otolaryngology Department of Daye People's Hospital were selected and randomly divided into a drug group and an atomization group,with 42 cases in each group.The drug group received general drug treatment,and the atomization group received budesonide suspension atomization inhalation treatment.The clinical efficacy,disease symptom subsidence time,inflammatory factor levels before and after treatment,and adverse reactions were compared between the two groups.Results:The effective rate of the atomization group was higher than that of the drug group,and the difference was statistically significant(P<0.05).The subsidence time of cough,systemic fever,sore throat and hoarseness in the atomization group was shorter than that in the drug group,and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the levels of TNF-α,IL-6 and CRP between the two groups(P>0.05);after treatment,the levels of TNF-α,IL-6 and CRP in the atomization group were lower than those in the drug group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the atomization group was lower than that in the drug group,and the difference was statistically significant(P<0.05).Conclusion:After applying budesonide suspension atomization inhalation in the treatment of acute pharyngitis patients,the clinical efficacy of the patients has been significantly improved.While improving the level of inflammatory factors,it can quickly shorten the time of disease-related symptoms.After applying budesonide suspension atomization inhalation treatment,the incidence of adverse reactions of patients has been significantly reduced,and the pain caused by the disease has been alleviated.Its clinical application value is high,and it is worthy of popularization.
作者
石清华
Shi Qing-hua(Otolaryngology Department,Daye People's Hospital,Daye 435100,Hubei Province,China)
出处
《中国社区医师》
2022年第25期10-12,共3页
Chinese Community Doctors
关键词
急性咽喉炎
布地奈德混悬液
雾化吸入
Acute pharyngitis
Budesonide suspension
Atomization inhalation
