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血小板/淋巴细胞比值联合平均血小板体积检测对ST段抬高型心肌梗死患者经皮冠脉介入术后无复流的预测价值 被引量:4

Predictive value of platelet/lymphocyte ratio combined with mean platelet volume detection in patients with ST-segment elevation myocardial infarction with no-reflow after percutaneous coronary intervention
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摘要 目的探讨血小板/淋巴细胞比值(PLR)联合平均血小板体积(MPV)检测对ST段抬高型心肌梗死(STEMI)患者经皮冠脉介入术(PCI)后无复流的预测价值。方法选取2019年8月至2021年10月杭州市第九人民医院收治的行PCI治疗的86例STEMI患者。统计STEMI患者PCI后无复流的发生情况,并将其分为无复流组和复流组。比较两组的临床资料,分析影响STEMI患者PCI后无复流的危险因素;分析PLR联合MPV检测对STEMI患者PCI后无复流发生的预测效能。结果STEMI患者PCI后无复流发生率为24.42%。无复流组低密度脂蛋白胆固醇、PLR及MPV高于复流组(P<0.05),左室射血分数低于复流组(P<0.05)。PLR、MPV为STEMI患者PCI后无复流的影响因素(OR>1,P<0.05)。联合检测的曲线下面积高于PLR、MPV单独检测。结论PLR联合MPV检测对STEMI患者PCI后无复流的预测效能较高。 Objective To explore the predictive value of platelet/lymphocyte ratio(PLR)combined with mean platelet volume(MPV)detection in patients with ST-segment elevation myocardial infarction(STEMI)with no-reflow after percutaneous coronary intervention(PCI).Methods A total of 86 STEMI patients who underwent PCI in Hangzhou Ninth People’s Hospital from August 2019 to October 2021 were selected,and all patients underwent PCI.The incidence of no-reflow in STEMI patients after PCI was statistically analyzed,and they were divided into no-reflow group and reflow group.The clinical data of two groups were compared,and the risk factors of no-reflow in STEMI patients after PCI were analyzed;and the predictive efficacy of PLR combined with MPV in the occurrence of no-reflow in STEMI patients after PCI was analyzed.Results The incidence of no-reflow in STEMI patients after PCI was 24.42%.The low-density lipoprotein cholesterol,PLR,and MPV in no-reflow group were higher than those in reflow group(P<0.05),while the left ventricular ejection fraction was lower than that in reflow group(P<0.05).PLR and MPV were the influencing factors of no-reflow in STEMI patients after PCI(OR>1,P<0.05).The area under the curve of combined detection was higher than that of PLR and MPV alone.Conclusion The combination of PLR and MPV has high predictive performance for no-reflow in STEMI patients after PCI.
作者 范玲珑 张义林 FAN Linglong;ZHANG Yilin(Department of Cardiovascular Medicine,Hangzhou Ninth People’s Hospital,Zhejiang Province,Hangzhou 311225,China)
出处 《中国医药导报》 CAS 2022年第26期67-70,共4页 China Medical Herald
基金 浙江省医药卫生科技计划项目(2020KY822)。
关键词 血小板/淋巴细胞比值 平均血小板体积 ST段抬高型心肌梗死 经皮冠脉介入术 Platelet/lymphocyte ratio Mean platelet volume ST-segment elevation myocardial infarction Percutaneous coronary intervention
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