摘要
目的探讨儿童过敏性紫癜(HSP)的临床特征,并分析复发的影响因素。方法回顾性分析2019年12月至2021年3月于河南科技大学第一附属医院进行治疗的82例HSP患儿的临床资料,探讨其临床特征,随访1年,按照是否复发分为复发组与未复发组,并对比分析两组患儿的一般临床资料,研究影响HSP患儿复发的独立危险因素。结果 82例患儿中男女比为1∶1.4;HSP发病年龄集中于7~14岁,春季、冬季多发,异种蛋白饮食、上呼吸道感染是其发病主要诱因;患儿多有腹痛及皮疹症状,以脐周疼为主,多呈阵发性绞痛及隐痛。Logistic回归分析结果显示,反复性皮疹、未控制饮食、未预防用药、糖皮质激素治疗、未限制运动是影响HSP患儿治愈后复发的独立危险因素(P<0.05)。结论 HSP发病时间多集中在春季、冬季,学龄期为主要发病年龄段,有腹痛、皮疹症状,监测反复性皮疹、控制饮食、预防用药、糖皮质激素治疗、限制运动,可为预测HSP复发提供客观依据。
Objective To investigate the clinical characteristics of children with Henoch-Schonlein purpura(HSP),and to analyse the influencing factors of recurrence.Methods The general clinical data of 82 children with HSP admitted to the First Affiliated Hospital of Henan University of Science and Technology from December 2019 to March 2021 was retrospectively analyzed,and their clinical characteristics were discussed.The children were followed up for 1 year,and they were divided into recurrence group and non-recurrence group according to disease recurrence.The general clinical data of the two groups were comparatively analyzed to screen the independent risk factors for the recurrence of HSP.Results The male to female ratio in the 82 children was 1∶1.4.Most of the children with HSP aged 7-14 years.Spring and winter were the high-incidence seasons.Foreign protein diet and upper respiratory tract infection were main causes of the onset of HSP.Most of the children had abdominal pain and skin rashes,mainly periumbilical pain,mostly paroxysmal colic and dull pain.Results of Logistic regression analysis showed that recurrent skin rash,uncontrolled diet,no preventive medication,glucocorticoid therapy and unrestricted exercise were independent risk factors for recurrence of HSP in children after treatment(P<0.05).Conclusions HSP easily occurs in spring and winter in children of school age.Abdominal pain and skin rashes are main symptoms.Monitoring recurrent rashes,controlling diet,preventive medication,glucocorticoid treatment,and restricting exercise can provide an objective basis for predicting the recurrence of HSP.
作者
黄丹丹
马国瑞
侯珍珍
Huang Dandan;Ma Guorui;Hou Zhenzhen(Department of Pediatrics,the First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处
《中国实用医刊》
2022年第13期32-35,共4页
Chinese Journal of Practical Medicine
关键词
过敏性紫癜
患儿
临床特征
复发
Henoch-Schonlein purpura
Child
Clinical characteristic
Recurrence
