摘要
咽后淋巴结(RPLNs)位于咽后间隙,解剖位置深,周围毗邻颈内动脉、颈内静脉、迷走神经等重要而复杂的血管、神经结构,因此,恶性肿瘤发生RPLNs转移时难以通过病理组织活检诊断,主要依靠磁共振成像(MRI)检查。恶性肿瘤RPLNs转移尚无标准的治疗方法,目前常采用放射治疗、手术治疗、化学治疗、免疫治疗、靶向治疗等。手术切除是重要手段。手术入路包括开放入路、内镜辅助入路及机器人辅助入路,其中内镜经口经翼下颌皱襞内侧(ETO-MPF)入路RPLNs切除术是近期应用于临床的一种微创、精准、安全的手术方法,是目前较为理想的手术方案,具有重要的临床意义。
Retropharyngeal lymph nodes(RPLNs) are located in the retropharyngeal space. RPLNs are adjacent to important and complex vascular and neural structures such as internal carotid artery, internal jugular vein and vagal nerve. It is difficult to be diagnosed by biopsy when RPLNs metastasis occurs. The diagnosis mainly depends on magnetic resonance imaging(MRI). The treatments of RPLNs metastasis of malignant tumors include radiotherapy, surgery, chemotherapy, immunotherapy, targeted therapy, etc., and there is no standard treatment. Surgical resection is an important treatment for RPLNs metastasis. The surgical approaches include open approach, endoscopic-assisted approach and robot-assisted approach. Meanwhile,endoscopic transoral-medial pterygomandibular fold(ETO-MPF) approach is a minimally invasive, accurate and safe surgical method. It is a relatively ideal surgical scheme at present and has important clinical significance.
作者
余洪猛
薛凯
孙希才
张焕康
刘全
赵可庆
顾晔
宋小乐
YU Hongmeng;XUE Kai;SUN Xicai;ZHANG Huankang;LIU Quan;ZHAO Keqing;GU Ye;SONG Xiaole(Department of Otolaryngology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China;Research Units of New Technologies of Endoscopic Surgery in Skull Base Tumor(2018RU003),Chinese Academy of Medical Sciences,Shanghai 200031;Department of Neurosurgery,Eye&ENT Hospital,Fudan University,Shanghai 200031,China)
出处
《中国眼耳鼻喉科杂志》
2022年第5期479-484,共6页
Chinese Journal of Ophthalmology and Otorhinolaryngology
基金
中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-003)
上海市科学技术委员会科技创新行动计划临床医学项目(No.19411950600)
上海市科学技术委员会/生物医药处/西医引导项目(20Y11902000)
上海市卫生局/局级项目(201940143)
上海申康医院发展中心/诊疗技术项目(SHDC22021214)。
关键词
咽后淋巴结
咽后间隙
鼻咽癌
内镜经口
Retropharyngeal lymph nodes
Retropharyngeal space
Nasopharyngeal carcinoma
Endoscopic transoral
