摘要
目的观察健康孕产妇和妊娠期高血压孕产妇在不同妊娠周期的肾素与醛固酮变化趋势,分析早期监测肾素、醛固酮对妊娠晚期血压、分娩结局的预防作用,评估预防性干预对妊娠期高血压患者结局的改善价值。方法采取回顾性分析法,选取我院2021年1~6月接收的60名健康孕产妇为正常组,以同期接收的60例妊娠期高血压孕产妇作为观察组,并以2020年7~12月接收的60例妊娠期高血压孕产妇作为对照组。在正常组与观察组孕产妇的不同妊娠周期测定肾素、醛固酮水平,观察2项指标的变化趋势。同时,针对观察组患者开展预防性干预措施,比较对照组与观察组孕产妇的血压水平及分娩结局。结果观察组产妇在12±1周、20±1周、28±1周、36±1周的肾素与醛固酮水平均低于正常组,比较差异有统计学意义(P<0.05)。观察组孕产妇在妊娠28±1周、36±1周的舒张压与收缩压水平均低于对照组,比较差异有统计学意义(P<0.05)。两组的胎儿窘迫、羊水异常、产后出血发生率比较,差异无统计学意义(P>0.05);观察组的早产发生率与剖宫产率均低于对照组,比较差异有统计学意义(P<0.05)。结论妊娠期高血压孕产妇在不同妊娠周期的肾素与醛固酮水平均为低表达,针对此类孕产妇开展预防性干预措施,持续监测其肾素、醛固酮水平,并采取预防对策,能够良好的控制妊娠晚期血压水平,改善分娩结局。
Objective To observe the change trend of renin and aldosterone in healthy pregnant women and pregnant women with gestational hypertension in different pregnancy cycles,analyze the preventive effect of early monitoring of renin and aldosterone on blood pressure during late pregnancy and delivery outcome,and evaluate the improvement value of preventive intervention on the outcome of patients with gestational hypertension.Methods By retrospective analysis,60 cases of healthy pregnant women received in our hospital from January to June 2021 were selected as the normal group,60 cases of pregnant women with gestational hypertension received in the same period were selected as the observation group,and 60 cases of pregnant women with gestational hypertension received from July to December 2020 were selected as the control group.The levels of renin and aldosterone were measured in the normal group and the observation group during different pregnancy cycles,and the trends of the two indexes were observed.Meanwhile,preventive intervention measures were carried out for the observation group,and blood pressure levels and delivery outcomes of pregnant women in the control group and observation group were compared.Results The levels of renin and aldosterone in the observation group were lower than those in the normal group at 12±1 week,20±1 week,28±1 week and 36±1 week,the differences were statistically significant(P<0.05).The diastolic blood pressure and systolic blood pressure of pregnant women in the observation group at 28±1 week and 36±1 week of gestation were lower than those in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the incidence of fetal distress,abnormal amniotic fluid and postpartum hemorrhage between the two groups(P>0.05).However,the incidence of premature delivery and cesarean section in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The levels of
作者
张曦
ZHANG xi(General Hospital of Fengcheng Mining Bureau,Fengcheng 331141,China)
出处
《中国医药指南》
2022年第26期78-81,共4页
Guide of China Medicine
关键词
妊娠期高血压
肾素
醛固酮
预防性干预
Gestational hypertension
Renin
Aldosterone
Preventive intervention
