摘要
目的 探讨维持性腹膜透析(peritoneal dialysis,PD)患者失眠发生的影响因素及中医证候分型情况。方法 选择2019年9至12月在温州市中医院和温州市中心医院规律随访的PD患者171例为研究对象,收集患者的临床数据及填写匹兹堡睡眠质量指数量表(Pittsburgh sleep quality index,PSQI),并进行中医证候分型,分析PD患者失眠的发生情况、影响因素及中医证候分型。结果 PD患者失眠发生率为45.03%。年龄大、血清尿素氮(blood urea nitrogen,BUN)高、总尿素清除指数(Kt/V)低是导致PD患者发生失眠的影响因素。失眠组本虚证以气阴两虚证(42.86%)为主要证型,标实证以血瘀证(47.22%)为主要证型;而非失眠组本虚证以脾肾气虚证(53.19%)为主要证型,标实证以湿浊证(47.73%)为主要证型。结论 年龄大、BUN高和透析不充分可能是PD患者发生失眠的影响因素。PD患者发生失眠患者的中医证候分型分布特点:失眠组本虚证以气阴两虚证为主要证型,标实证以血瘀证为主要证型。非失眠组本虚证型以脾肾气虚证为为主要证型,标实证以湿浊证为主要证型。
Objective To analyze the influencing factors of insomnia in maintenance peritoneal dialysis patients and the distribution characteristics of traditional Chinese medicine(TCM) syndromes. Methods A cross-sectional study method was used to investigate 171 patients with maintenance PD. The clinical data of the patients were collected and the Pittsburgh Sleep Quality Index table was filled. The TCM syndrome classification was carried out according to the TCM syndrome classification table, and statistical analysis was performed to obtain the PD patients. Occurrence of insomnia, related factors and distribution characteristics of syndromes. Results The incidence of insomnia in PD patients in this survey was 45.03%. Older age, higher blood urea nitrogen(BUN) and lower total urea clearance index(Kt/V) were the influencing factors of insomnia in PD patients. In insomnia group, Qi Yin deficiency syndrome(42.86%) was the main syndrome type, and blood stasis syndrome(47.22%) was the main syndrome type, However, in non insomnia group, spleen and kidney Qi deficiency syndrome(53.19%) was the main syndrome type, and dampness turbidity syndrome(47.73%) was the main syndrome type. Conclusion Older age, higher bun and insufficient dialysis may be the influencing factors of insomnia in PD patients. Distribution characteristics of TCM syndrome types in patients with PD combined with insomnia. In the insomnia group, the proportion of qi and yin deficiency syndromes is the highest, and the standard syndrome is blood stasis syndrome. In the non-insomnia group, the spleen-kidney qi deficiency syndrome had the most cases, and the standard syndrome type had the most cases of damp-turbidity syndrome.
作者
陈春
邵思思
陈辉
王婷婷
黄蔚霞
CHEN Chun;SHAO Sisi;CHEN Hui;WANG Tingting;HUANG Weixia(Department of Nephrology,Wenzhou Hospital of Traditional Chinese Medicine,Zhejiang University of Traditional Chinese Medicine,Zhejiang,Wenzhou 325000,China;Department of Nephrology,Wenzhou Central Hospital,Zhejiang,Wenzhou 325000,China)
出处
《中国现代医生》
2022年第23期43-46,50,共5页
China Modern Doctor
基金
温州市科学技术局项目(Y202095)。
关键词
维持性腹膜透析
失眠
影响因素
中医证候分型
Maintenance peritoneal dialysis
Insomnia
influencing factors
TCM certificate type
