摘要
目的:分析采用微创导管溶栓术(CDT)联合利伐沙班治疗急性下肢深静脉血栓的临床疗效。方法:选取2019年3月-2022年3月重庆市江津区第二人民医院收治的急性下肢深静脉血栓患者40例为观察对象,按治疗方法不同分为对照组与观察组,各20例。对照组予单纯利伐沙班治疗,观察组予微创CDT联合利伐沙班治疗。比较两组治疗前、治疗7 d后、1个月后的患侧与健侧大小腿周径差、髂股静脉再通情况、住院时间与并发症发生情况。结果:治疗前,两组大小腿周径差比较,差异无统计学意义(P>0.05);治疗7 d后,观察组大小腿周径差低于对照组,治疗1个月后,观察组周径差低于对照组,差异有统计学意义(P<0.05);观察组髂股静脉通畅评分低于对照组,住院时间短于对照组,差异有统计学意义(P<0.05);观察组并发症低于对照组,差异无统计学意义(P>0.05)。结论:微创CDT联合利伐沙班治疗急性下肢深静脉血栓能够有效降低大小腿周径差,加速血栓溶解,且不会增加并发症发生率,是一种安全、有效的治疗手段。
Objective: To analyze the clinical efficacy of minimally invasive catheter thrombolysis (CDT) combined with rivaroxaban in the treatment of acute lower extremity deep vein thrombosis. Methods: Forty patients with acute lower extremity deep vein thrombosis admitted to the Second People′s Hospital of Jiangjin District of Chongqing from March 2019 to March 2022 were selected as the observation subjects. According to different treatment methods, they were divided into control group and observation group, with 20 cases in each group. The control group was treated with rivaroxaban alone and the observation group was treated with minimally invasive CDT combined with rivaroxaban. Before treatment, 7 days after treatment, and 1 month after treatment, the circumference differences of the thigh and lower leg between the affected side and the healthy side, the recanalization of the iliofemoral vein, the length of hospital stay, and the incidence of complications in two groups were compared. Results: Before treatment, there was no significant difference in the circumference differences of the thigh and lower leg between the two groups (P>0.05);after 7 days of treatment, the circumference differences of the thigh and lower leg in the observation group were lower than those in the control group, and after 1 month of treatment, the circumference differences in the observation group were lower than those in the control group, with statistically significant difference (P<0.05). The iliofemoral vein patency score of the observation group was lower than that of the control group, and the length of hospital stay was shorter than that of the control group, and the difference was statistically significant (P<0.05). The complications in the observation group were lower than those in the control group, and the difference was not statistically significant(P>0.05). Conclusion: Minimally invasive CDT combined with rivaroxaban in the treatment of acute lower extremity deep venous thrombosis can effectively reduce the circumference differen
作者
熊卫平
兰翠茹
杜丛林
刘艳茹
盛华
胡庆龄
杨鑫磊
曹霞
余越
Xiong Wei-ping;Lan Cui-ru;Du Cong-lin;Liu Yan-ru;Sheng Hua;Hu Qing-ling;Yang Xin-lei;Cao Xia;Yu Yue(The Second People's Hospital of Jiangjin District of Chongqing,Chongqing 402283,China)
出处
《中外医药研究》
2022年第3期36-38,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
重庆市江津区科技计划项目(编号:Y2020113)。
关键词
急性下肢深静脉血栓
微创导管溶栓术
利伐沙班
Acute lower extremity deep vein thrombosis
Minimally invasive catheter thrombolysis
Rivaroxaban
