摘要
目的研究咽鼓管球囊扩张术与鼓膜切开术治疗鼻咽癌放射性治疗后咽鼓管功能障碍的效果。方法选取142例鼻咽癌放射性治疗后发生咽鼓管功能障碍的患者作为研究对象,采用随机数字表法分为实验组(n=71)和对照组(n=71),对照组接受鼓膜切开术治疗,实验组接受咽鼓管球囊扩张术。对比2组临床疗效;对比2组手术前后七项咽鼓管功能障碍症状评分量表(ETDQ-7)和疼痛程度;对比2组患者术后出现的不良反应。结果与对照组总有效率88.73%(63/71)相比,实验组总有效率98.59%(70/71)显著更高(P<0.05)。手术后,2组患者ETDQ-7评分均降低,且相比于对照组,实验组显著更低(P<0.05);手术后,2组患者疼痛视觉模拟评分法(VAS)评分均降低,且相比于对照组,实验组显著更低(P<0.05)。与对照组不良反应发生率11.26%(8/71)相比,实验组2.80%(2/71)显著更低(P<0.05)。结论相比于鼓膜切开术,咽鼓管球囊扩张术对鼻咽癌放射性治疗后咽鼓管功能障碍的疗效更佳,可明显改善患者咽鼓管功能障碍和疼痛程度,且不良反应较低。
Objective To compare the effect of balloon eustachian tuboplasty and myringotomy in the treatment of eustachian tube dysfunction after radiotherapy for nasopharyngeal carcinoma.Methods A total of 142 patients with eustachian tube dysfunction after radiotherapy for nasopharyngeal carcinoma were enrolled,and divided into 2 groups by random number table methods,each with 71 cases.The control group received myringotomy,while the experimental group received balloon eustachian tuboplasty.Then the clinical outcomes,Eustachian Tube Dysfunction Questionnaire-7(ETDQ-7)score,Visual Analogue Scale(VAS)score,and adverse reaction rate were compared between the 2 groups.Results The clinical efficacy rate was 98.59%(70/71)in the experimental group,which was significantly higher than 88.73%(63/71)in the control group,with statistical difference(P<0.05).After operation,scores of ETDQ-7 and VAS were decreased in both groups(P<0.05),and the scores were significantly lower in experimental group than in the control group(P<0.05).The adverse reaction rate was 2.80%(2/71)in the experimental group,which was significantly lower than 11.26%(8/71)in the control group,with statistical difference(P<0.05).Conclusion Compared with myringotomy,application of balloon eustachian tuboplasty can effectively ameliorate the clinical symptoms and alleviate the pain in patients with eustachian tube dysfunction after radiotherapy for nasopharyngeal carcinoma,without increasing the adverse reactions.
作者
李晓玲
魏鑫鑫
王晴晴
LI Xiaoling;WEI Xinxin;WANG Qingqing(Nanyang Central Hospital,Nanyang,473000)
出处
《实用癌症杂志》
2022年第9期1557-1560,共4页
The Practical Journal of Cancer
关键词
咽鼓管球囊扩张术
鼓膜切开术
放射性治疗
咽鼓管功能
Balloon eustachian tuboplasty
Myringotomy
Radiation therapy
Eustachian tube function
