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子宫颈环扎术或孕酮治疗宫颈长度<10 mm单胎妊娠效果对比

Comparison of effect of cervical cerclage and progesterone for treating singleton pregnant women with short cervix(<10 mm)
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摘要 目的:对比分析子宫颈环扎术或孕酮治疗短子宫颈(<10 mm)单胎妊娠效果。方法:回顾性收集2018年6月-2021年6月在本院收治的子宫颈<10 mm的单胎妊娠孕妇资料132例,按照不同治疗方式分为环扎术组(n=83,子宫颈环扎术治疗)和孕酮组(n=49,孕酮治疗)。比较两组累计分娩率、妊娠情况、新生儿情况、并发症发生率。结果:两组分娩方式无差异(P>0.05),环扎术组妊娠≥37周累积分娩率(81.9%)高于孕酮组(63.3%),分娩孕周(36.6±2.1周)及妊娠延长时间(20.4±3.7周)均长于孕酮组(35.6±2.3周、19.1±3.8周)(均P<0.05);两组新生儿存活率无差异(P>0.05),环扎术组新生儿出生体重(2.8±0.4kg)高于孕酮组(2.5±0.4kg),转新生儿科比例(15.7%)少于孕酮组(34.7%),新生儿Apgar评分(8.0±1.4分)高于孕酮组(7.5±1.2分)(P<0.05),并发症发生率(12.1%)与孕酮组(10.2%)无差异(P>0.05)。结论:宫颈环扎术治疗宫颈<10 mm单胎妊娠效果高于孕酮治疗,治疗过程中合理使用抗感染及抑制宫缩药物、定期监测孕妇阴道分泌物等可降低环扎术后感染及早产发生率。 Objective:To compare and analyze the effect of cervical cerclage and progesterone for treating singleton pregnant women with short cervix(<10 mm).Methods:132 singleton pregnant women with short cervix(<10 mm)between June 2018 and June 2021 were collected retrospectively.These women were divided into group A(83 cervical cerclage treatment)and group B(49 women with progesterone treatment)according to different treatment methods.The cumulative delivery rate,the pregnancy status,the neonatal status,and the incidence of complications of the women were compared between the two groups.Results:There was no significant difference in the delivery mode of the women between the two groups(P>0.05).The cumulative delivery rate(81.9%)of the women during≥37 gestational weeks in group A was significantly higher than that(63.3%)of the women in group B,the gestational weeks at delivery(36.6±2.1 weeks)and the gestational prolongation time(20.4±3.7 weeks)of the women in group A were significantly longer than those(35.6±2.3 weeks and 19.1±3.8 weeks)of the women in group B(all P<0.05).There was no significant difference in the neonatal survival rate between the two groups(P>0.05).The birth weight of neonates(2.8±0.4kg)in group A was significantly higher than that(2.5±0.4kg)in group B,the proportion of the neonates transferred in neonatal department(15.7%)in group A was significantly lower than that(34.7%)of the neonates in group B,and the neonatal Apgar score(8.0±1.4 points)in group A was significantly higher than that(7.5±1.2 points)in group B(P<0.05).There was no significant difference in the complication rate(10.2%vs.12.1%)of the women between the two groups(P>0.05).Conclusion:The effect of cervical cerclage for treating singleton pregnant women with short cervix<10 mm is higher than that of progesterone treatment.The rational use of drugs for anti-infection and control uterine contraction,and regular monitoring vaginal secretions situation of these pregnant women can reduce their rate of infection after cerclage and can d
作者 周洁 朱晓红 戚婷婷 李霞 翁晓菁 孙丽洲 ZHOU Jie;ZHU Xiaohong;QI Tingting;LI Xia;WENG Xiaojing;SUN Lizhou(The First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu Province,210029;Huai'an Maternal and Child Health Care Hospital)
出处 《中国计划生育学杂志》 2022年第9期1992-1996,共5页 Chinese Journal of Family Planning
基金 淮安市卫生健康科研项目(HAWJZ202003)。
关键词 短子宫颈 单胎妊娠 子宫颈环扎术 孕酮 新生儿 感染 Short cervix Singleton pregnancy Cervical cerclage Progesterone Neonate Infection
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