摘要
目的探索右正中神经电刺激联合高压氧对颅脑外伤促醒作用及认知功能与脑血流的影响。方法前瞻性纳入南阳南石医院2021-01—2021-07收治的122例颅脑外伤患者,根据随机数字表法分为2组,对照组61例采用右正中神经电刺激治疗,观察组61例采用右正中神经电刺激联合高压氧治疗,均治疗6个疗程后,比较2组治疗效果。结果观察组治疗后6个疗程的rCBV(3.56±0.67)mL/100 g、rCBF(43.57±5.22)mL/100 g、Vm(55.42±5.42)cm/s、Vp(68.42±4.51)m/s以及脑干血流灌注(8.88±1.44)mL/(min·100 g)、丘脑血流灌注(12.56±1.82)mL/(min·100 g)、皮层区域血流灌注(13.58±2.37)mL/(min·100 g)改善情况优于对照组(P<0.05),治疗后1个疗程、3个疗程、6个疗程的疾病改善率分别为50.82%、73.77%、95.08%均高于对照组(P<0.05)。同时观察组治疗后3个疗程和6个疗程的GCS评分、MMSE评分也高于对照组(P<0.05)。结论对颅脑外伤患者实施右正中神经电刺激联合高压氧治疗,能够提高脑血流量,改善认知功能。
Objective To explore the effect of electrical stimulation of right median nerve combined with hy⁃perbaric oxygen on awakening effects of traumatic brain injury,cognitive function and cerebral blood flow.Methods Prospectively enrolled 122 cases of craniocerebral trauma patients were admitted between January 2021 and July 2021.They were divided into two groups according to the random number table method.Sixty-one cases of the con⁃trol group were treated with electrical stimulation of the right median nerve,and the observation group sixty-one pa⁃tients were treated with right median nerve electrical stimulation combined with hyperbaric oxygen therapy.After 6 courses of treatment,the therapeutic effects of the two groups were compared.Results The observation group’s rCBV(3.56±0.67)mL/100 g,rCBF(43.57±5.22)mL/100 g,Vm(55.42±5.42)cm/s,Vp(68.42±4.51)m/s and 6 courses after treatment in the observation group brainstem blood perfusion(8.88±1.44)mL/(min·100 g),thalamic blood perfusion(12.56±1.82)mL/(min·100 g),cortical area blood perfusion(13.58±2.37)mL/(min·100 g)im⁃proved better than In the control group(P<0.05),the disease improvement rates of 1 course,3 courses,and 6 courses after treatment were 50.82%,73.77%,and 95.08%,which were higher than those of the control group(P<0.05).At the same time,the GCS scores and MMSE scores of the observation group were higher than those of the control group for 3 courses and 6 courses after treatment(P<0.05).Conclusion Applying right median nerve electrical stimulation combined with hyperbaric oxygen therapy to patients with craniocerebral trauma can increase cerebral blood flow and improve cognitive function.
作者
闫峰
杨荣刚
沈江宜
YAN Feng;YANG Ronggang;SHEN Jiangyi(Nanyang Nanshi Hospital,Nanyang 473000,China)
出处
《中国实用神经疾病杂志》
2022年第8期946-952,共7页
Chinese Journal of Practical Nervous Diseases
关键词
颅脑外伤
正中神经电刺激
高压氧
促醒
认知功能
脑血流
Craniocerebral trauma
Median nerve electrical stimulation
Hyperbaric oxygen
Awakening
Cognitive function
Cerebral blood flow
