摘要
目的评估脂质蓄积指数(LAP)和内脏脂肪指数(VAI)筛查代谢综合征(MS)的价值。方法基于2018年山东省烟台市慢性病及危险因素调查,收集≥45岁人群的年龄、疾病史、腰围(WC)、体质指数(BMI)、血压和血脂资料,计算LAP和VAI。分别采用国际多机构关于MS定义的联合声明(JIS标准)和中华医学会糖尿病分会推荐标准(CDS标准)诊断MS,绘制受试者操作特征(ROC)曲线评估LAP和VAI筛查MS的价值。结果纳入9366人,年龄为(59.49±9.73)岁。男性4340人,占46.34%;女性5026人,占53.66%。按照CDS标准诊断,MS患病率为24.58%;LAP和VAI筛查MS的曲线下面积(AUC)分别为0.837(95%CI:0.828~0.846)和0.751(95%CI:0.739~0.762),灵敏度分别为78.82%和63.31%,最佳截断值分别为44.64和1.86。按照JIS标准诊断,MS患病率为35.26%;LAP和VAI筛查MS的AUC值分别为0.842(95%CI:0.834~0.850)和0.790(95%CI:0.780~0.800),灵敏度分别为75.73%和68.42%,最佳截断值分别为42.01和1.67。结论LAP和VAI筛查中老年人群MS的准确性较好,LAP要优于VAI。
Objective To investigate the value of lipid accumulation product(LAP)and visceral fat index(VAI)for prediction of metabolic syndrome(MS).Methods Based on the 2018 Survey on Chronic Diseases and Risk Factors in Yantai City of Shandong Province,residents at ages of 45 years and older were sampled,and subjects'age,disease history,waist circumstance(WC),body mass index(BMI),blood pressure and blood lipid were collected to calculate LAP and VAI.MS was diagnosed with the a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention;National Heart,Lung,and Blood Institute;American Heart Association;World Heart Federation;International Atherosclerosis Society;and International Association for the Study of Obesity(JIS definition)and the recommended criteria proposed by the Chinese Diabetes Society(CDS)of Chinese Medical Association(CDS criteria),and the values of LAP and VAI for MS screening were evaluated using the receiver operating characteristic(ROC)curve analysis.Results Totally 9366 subjects were enrolled,including 4340 men(46.34%)and 5026 women(53.66%),and had a mean age of(54.49±9.73)years.According to the CDS criteria,the prevalence of MS was 24.58%,and LAP and VAI showed areas under the ROC curve(AUC)of 0.837(95%CI:0.828-0.846)and 0.751(95%CI:0.739-0.762),sensitivities of 78.82%and 63.31%and optimal cut-off values of 44.64 and 1.86 for screening of MS.According to the JIS definition,the prevalence of MS was 35.26%,and LAP and VAI showed AUC values of 0.842(95%CI:0.834-0.850)and 0.790(95%CI:0.780-0.800),sensitivities of 75.73%and 68.42%and optimal cut-off values of 42.01 and 1.67 for screening of MS.Conclusions Both LAP and VAI are effective for screening MS among middle-aged and elderly residents,and LAP presents a higher accuracy than VAI.
作者
王倩倩
曲淑娜
于绍轶
张红杰
WANG Qianqian;QU Shuna;YU Shaoyi;ZHANG Hongjie(Department of Non-communicable Disease Control and Prevention,Yantai Center for Disease Control and Prevention,Yantai,Shandong 264003,China)
出处
《预防医学》
2022年第9期928-931,共4页
CHINA PREVENTIVE MEDICINE JOURNAL
基金
山东省医药卫生科技发展计划项目(202012050192)。
关键词
脂质蓄积指数
内脏脂肪指数
代谢综合征
中老年人群
lipid accumulation product
visceral fat index
metabolic syndrome
middle-aged and elderly people
