摘要
[目的]探讨甲硝唑联合克林霉素治疗母牛细菌性阴道炎的临床效果。[方法]将确诊患有细菌性阴道炎的病牛25头,分为3组。Ⅰ组为观察组,患病母牛11头,用甲硝唑和克林霉素治疗;Ⅱ组为对照组1,患病母牛6头,用甲硝唑治疗;Ⅲ组为对照组2,患病母牛8头,用克林霉素治疗。甲硝唑注射液,5~6 g/头,24 h/次,连用5 d,静脉滴注;克林霉素,1.5~2 g/头,24 h/次,连用5 d,静脉滴注。治疗1个疗程后,对治愈母牛进行发情观察和人工授精配种。[结果]①观察组临床治疗有效率为90.91%,显著高于对照组1(80.33%)和对照组2(75.00%)(P<0.05);②观察组平均治疗效果为72.25%,显著高于对照组1(64.92%)和对照组2(57.89%)(P<0.05);③观察组、对照组1、对照组2和健康对照组牛发情率分别为81.82%,83.33%,75.00%和87.50%,观察组、对照组1和健康对照组显著优于对照组2,观察组、对照组1和健康对照组无显著差异;配种受胎率分别为72.72%,66.67%,62.50%和75.00%,观察组、健康对照组显著优于对照组1和对照组2(P<0.05);产活犊率分别为100%,75%,80%和100%,观察组、健康对照组显著优于对照组1和对照组2(P<0.05)。[结论]甲硝唑联合克林霉素治疗母牛细菌性阴道炎疗效显著,药物安全性高,不影响母猪的繁殖性能,具有临床推广价值;甲硝唑、克林霉素次之。
[Objective] To investigate the clinical effect of metronidazole combined with clindamycin in the treatment of cow bacterial vaginitis. [Method] 25 cattle with bacterial vaginitis were divided into three groups. Group Ⅰ was the observation group, 11 cows were treated with metronidazole and clindamycin. Group Ⅱ was control group 1, with 6 sick cows treated with metronidazole. Group Ⅲ was control group 2, with 8 sick cows treated with clindamycin. Metronidazole Injection, 5~6 g/head, 24 h/time, continuous use for 5 d, intravenous drip. Clindamycin, 1.5~2 g/head, 24 h/time, continuous use for 5 days, intravenous drip. After one course of treatment, the cured cows were observed for estrus and artificially inseminated. [Result]① The clinical effective rate of the observation group was 90.91%, which was significantly higher than that of the control group 1(80.33%) and the control group 2(75.00%)(P< 0.05).② The average treatment effect of the observation group was 72.25%, which was significantly higher than that of the control group 1(64.92%) and the control group 2(57.89%)(P< 0.05).③ The oestrus rates of the observation group, the control group 1, the control group 2 and the healthy control group were 81.82%, 83.33%, 75.00% and 87.50% respectively. The observation group, the control group 1 and the healthy control group were significantly better than the control group 2, and there was no significant difference between the observation group, the control group 1 and the healthy control group. The conception rates of mating were 72.72%, 66.67%, 62.50% and 75.00% respectively. The observation group and healthy control group were significantly better than control group 1 and control group 2(P< 0.05). The live calving rates were 100%, 75%, 80% and 100% respectively. The observation group and healthy control group were significantly better than control group 1 and control group 2(P< 0.05). [Conclusion] Metronidazole combined with clindamycin is effective and safe in the treatment of bovine bacterial vaginitis, whic
作者
吴宽林
严业广
刘家力
张玉西
WU Kuan-lin;YAN Ye-guang;LIU Jia-li;ZHANG Yu-xi(Agricultural and Rural Service Center of Guiling Town,Babu District,Hezhou City,Hezhou,Guangxi 542806;Agricultural and Rural Service Center of Nanxiang Township,Babu District,Hezhou City,Hezhou,Guangxi 542805;Agricultural and Rural Service Center,Huangtian Town,Pinggui District,Hezhou City,Hezhou,Guangxi 542807;Animal Husbandry Feed and Grassland Supervision Station,Babu District,Hezhou,Guangxi 542800)
出处
《中国牛业科学》
2022年第4期25-29,共5页
China Cattle Science
关键词
甲硝唑
克林霉素
细菌性阴道炎
疗效观察
metronidazole
clindamycin
bacterial vaginitis
curative effect observation
