摘要
目的观察温阳固本宣肺化痰汤治疗稳定期慢性阻塞性肺疾病(COPD)阳虚证的临床疗效。方法将60例辨证为阳虚的COPD患者分为温阳固本宣肺化痰汤治疗组30例和西药对照组30例,均治疗8周。观察治疗前后2组患者中医证候积分、临床疗效、第一秒用力呼气流量(FEV1)、FEV1占预计值%、用力肺活量(FVC)、慢性阻塞性肺病评估测试(CAT)评分、修订的呼吸困难量表(mMRC)评分的变化。结果治疗组与对照组临床疗效、CAT值比较,差异无统计学意义(P>0.05);治疗组FEV1、FEV1占预计值百分比、FVC值、mMRC值均优于对照组(P<0.05,P<0.01,P<0.001)。结论温阳固本宣肺化痰汤与西药的临床疗效相似,但在改善慢性阻塞性肺疾病稳定期阳虚证患者肺功能方面优于对照组,值得推广并深入研究。
Objective:To observe the clinical efficacy of Wenyang Guben Xuanfei Huatan Decoction in the treatment of stable chronic obstructive pulmonary disease(COPD)with yang deficiency syndrome.Methods:60 COPD patients with yang deficiency were divided into Wenyang Guben Xuanfei Huatan Decoction treatment group and western medicine control group,30 cases each group.Both groups were treated for 8 weeks.Before and after treatment,TCM syndrome scores,clinical efficacy,forced expiratory flow in one second(FEV1),FEV1%of predicted value,forced vital capacity(FVC),COPD assessment test(CAT)score,revised changes in dyspnea scale(mMRC)scores were observed.Results:There was no significant difference in the clinical efficacy and CAT value between the treatment group and the control group(P>0.05,P<0.01 and P<0.001).Conclusion:The clinical efficacy of Wenyang Guben Xuanfei Huatan Decoction is similar to that of western medicine,but the treatment group is better than the control group in improving the lung function of COPD patients with stable yang deficiency syndrome,which is worthy of promotion and further research.
作者
张春
吴文笛
杨秀美
刘军
曹雪
游顶云
武鸿翔
ZHANG Chun;WU Wen-di;YANG Xiu-mei;LIU Jun;CAO Xue;YOU Ding-yun;WU Hong-xiang(The First People's Hospital of Kunming City,Kunming 650011,China;Traditional Chinese Medicine Hospital of Kunming City,Kunming 650011,China;Kunming Medical University,Kunming 650500,China)
出处
《云南中医中药杂志》
2022年第8期35-38,共4页
Yunnan Journal of Traditional Chinese Medicine and Materia Medica
基金
国家自然科学基金项目(81760869)
云南省科技厅-昆明医科大学应用基础研究联合专项〔2018FE001(-284)〕。
关键词
温阳固本宣肺化痰汤
慢性阻塞性肺疾病
阳虚
临床研究
Wenyang Guben Xuanfei Huatan Decoction
Chronic Obstructive Pulmonary Disease
Yang Deficiency
Clinical Research
