摘要
格雷夫斯病是一种常见的自身免疫病,发病机制未明,儿童发病率明显低于成人,各地发病情况不一,但总体呈逐年增加趋势。实验室检查以甲状腺功能改变最为常见,临床表现除高代谢症状还可出现生长加速等表现。目前,儿童格雷夫斯病的治疗首选口服甲巯咪唑,治疗方便且不良反应较少,但需关注患儿缓解情况及疗程问题。对于长期口服抗甲状腺药物治疗仍未见好转的患儿,可考虑行放射性碘治疗,将明显提高患儿的缓解率。本文就儿童格雷夫斯病的相关情况进行综述。
Graves disease is a common autoimmune disease with unknown pathogenesis.The incidence of children is significantly lower than that of adults,the incidence varies from place to place,but the overall trend is increasing year by year.The most common laboratory test is the change of thyroid function,and the clinical manifestations include hypermetabolism symptoms and other manifestations such as accelerated growth.At present,oral Methimazole is the first choice for the treatment of children with Graves disease,which is convenient to treat and has few adverse reactions.For children who have not improved after long-term oral antithyroid drug treatment,iodine therapy can be considered,which will significantly improve the remission rate of children.This article reviews the status of Graves disease in children.
作者
石鸿娇
张祎俐
赵彤
崔岚巍
SHI Hongjiao;ZHANG Yili;ZHAO Tong;CUI Lanwei(Department of Pediatrics,the First Affiliated Hospital of Harbin Medical University,Heilongjiang Province,Harbin 150000,China)
出处
《中国医药导报》
CAS
2022年第22期39-41,共3页
China Medical Herald
基金
十三五慢性非传染性疾病防控研究重大专项项目(2016YFC1305301)。
