摘要
目的基于胸部CT定量测量探讨正常学龄前儿童肺内血管体积(IPVV)随生长发育的变化趋势。方法回顾性收集"数字肺"影像数据库2014年1月至2017年5月行胸部CT检查且结果正常的407例正常学龄前儿童的CT资料,男236例、女171例,月龄36(21,50)个月,范围1~72个月。使用"数字肺"肺血管自动检测工具分割肺内血管,并得到全肺、右肺、左肺及各肺叶的IPVV,计算IPVV上/下及IPVV左/右。根据月龄将受试者分为婴儿期(0~12个月)、幼儿期(13~36个月)和学龄前期(37~72个月),分别为30例(男17例、女13例)、175例(男95例、女80例)、202例(男124例、女78例)。用Spearman相关性分析评价IPVV与月龄的相关性。采用单因素方差分析或Kruskal-WallisH检验比较不同月龄段间、采用独立样本t检验或Mann-WhitneyU检验比较不同性别间IPVV、IPVV上/下及IPVV左/右的差异,并建立各个月龄段正常学龄前儿童IPVV的正常参考值范围。结果全肺、右肺、左肺及各个肺叶的IPVV与月龄均呈正相关,相关系数男性为0.638~0.820,女性为0.683~0.791(P均<0.001)。0~12个月的男、女童间全肺、右肺、左肺及各肺叶IPVV差异均无统计学意义(P均>0.05),13~36个月男、女童间全肺、右肺、左肺及各肺叶IPVV差异均有统计学意义(P均<0.05),37~72个月男、女童间全肺、右肺、左肺、双肺上叶IPVV差异均有统计学意义(P均<0.05)。男、女童3个月龄段间右肺IPVV上/下(χ^(2)=14.00、12.87,P=0.001、0.002)和左肺IPVV上/下差异均有统计学意义(χ^(2)=6.65、22.84,P=0.036、<0.001),且随着月龄的增长呈递减趋势;同月龄段男、女童间IPVV上/下差异无统计学意义(P均>0.05)。不同月龄段及各月龄段不同性别间IPVV左/右差异均无统计学意义(P均>0.05)。最后计算出婴儿期、幼儿期、学龄前期不同性别IPVV的正常参考值范围。结论正常学龄前儿童肺血管的增长与月龄呈正相关,婴儿期男、女间IPVV无显著�
Objective To investigate the development of intrapulmonary vascular volume(IPVV)in normal preschool children based on quantitative measurement on chest CT.Methods The CT data of 407 normal preschool children(236 males and 171 females,aged 1-72 months,with a median of 36 months)who underwent chest CT examination from January 2014 to May 2017 in the"Digital Lung"imaging database were retrospectively collected.The pulmonary vessels were segmented by the"Digital Lung"automatic detection tool,and the IPVV of the whole lung,the right lung,the left lung and each lobe were obtained,and the IPVVupper/lower and IPVVleft/right were calculated.According to the age,the subjects were divided into infant period(0-12 months),early childhood period(13-36 months)and preschool period(37-72 months),with 30 cases(17 males and 13 females),175 cases(95 males and 80 females)and 202 cases(124 males and 78 females)respectively.Spearman correlation analysis was used to evaluate the correlation between IPVV and month age.One-way analysis of variance or Kruskal-Wallis H test was used to compare the differences of IPVV,IPVVupper/lower and IPVVleft/right between different months of age.Independent sample t test or Mann-Whitney U test was used to compare the differences of IPVV between different genders,and the normal reference range of IPVV in normal preschool children of different months of age was established.Results The IPVV of the whole lung,right lung,left lung and each lung lobe were positively correlated with age,the correlation coefficient was 0.638-0.820 in males and 0.683-0.791 in females(all P<0.001).There was no significant difference in IPVV of whole lung,right lung,left lung and each lobe between male and female from 0 to 12 months(all P>0.05),but there was significant difference in IPVV of whole lung,right lung,left lung and each lobe between male and female from 13 to 36 months(all P<0.05).There were significant differences in IPVV of the whole lung,right lung,left lung and upper lobe of both lungs between boys and girls from 3
作者
李萌
沈聪
杨薇粒
银楠
问雷涛
郭佑民
Meng Li;Cong Shen;Weili Yang;Nan Yin;Leitao Wen;Youmin Guo(Department of Medical Imaging,the First Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710061,China;Department of Pediatric Surgery,the Second Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710004,China)
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2022年第8期873-878,共6页
Chinese Journal of Radiology
关键词
儿童
学龄前
体层摄影术
X线计算机
肺内血管体积
Child,preschool
Tomography,X-ray computed
Intrapulmonary blood vessel volume
