摘要
多发性骨髓瘤是以克隆性浆细胞增殖为特征的血液系统肿瘤。伴随新药和免疫治疗的发展,多发性骨髓瘤预后显著改善,半数以上患者将长期生存10年以上;因此,其疾病管理模式亟待优化。健康管理是慢性病防治的有效方法;疾病全周期健康管理理念要求健康管理应从疾病前期到终末期全过程实施。把全周期管理理念植入到多发性骨髓瘤的健康管理实践中,将有力且高效地指导并规范骨髓瘤疾病全周期健康管理工作切实推进。本文就多发性骨髓瘤疾病的全周期概念以及相应的健康管理内容进行综述。
Multiple myeloma is a hematologic tumor characterized by clonal proliferation of plasma cells.The development of novel agents and immunotherapy have substantially improved the prognosis of multiple myeloma, with an expectable median survival beyond ten years.Therefore, there is an urgent need to improve the management of this disease.Health management is effective in controlling chronic diseases and full-cycle management should be implemented from the early to the end stage of the disease.Implanting the full-cycle concept into the health management of multiple myeloma will guide and standardize the advances in this field.This review focuses on the full-cycle concept of multiple myeloma and the corresponding application of health management at each stage of the cycle.
作者
段嘉宇
崔健
唐文娇
邹忠晴
张丽
DUAN Jiayu;CUI Jian;TANG Wenjiao;ZOU Zhongqing;ZHANG Li(Institute of Hematology,Department of Hematology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2022年第4期673-677,共5页
Acta Academiae Medicinae Sinicae
基金
国家自然科学基金(81770218)
四川省自然科学基金(2022NSFSC1299)
四川省大学生创新创业训练计划(S202110610503)。
关键词
多发性骨髓瘤
全周期
健康管理
意义未明的单克隆免疫球蛋白血症
冒烟型骨髓瘤
multiple myeloma
full-cycle management
health management
monoclonal gammopathy of undetermined significance
smoldering multiple myeloma
