摘要
泰泽病原体(Tyzzer’s organism)是一种能引起实验动物肝肠坏死和腹泻的毛发状芽孢杆菌(Clostridium piliforme,旧称Bacillus piliformis)。该病原体引起的泰泽病是一种急性疾病,其发病迅速、致死率高、临床症状不明显,往往难以进行早期诊断和治疗,一旦爆发,将会造成严重的经济损失和实验室安全问题。本文从泰泽病原体的生物学特性、流行病学与疾病特征、检测方法、研究进展及防治多个方面进行综述。
Tyzzer's organism is a kind of Clostridium piliforme,formerly Bacillus piliformis,which can cause hepatointestinal necrosis and diarrhea in animals.Tyzzer's disease caused by this pathogen is an acute disease with rapid onset,high mortality and no obvious clinical symptoms,so it is difficult to make early diagnosis and treatment.Once the outbreak,it will cause irreparable economic losses and laboratory safety problems.This article reviewed the biological characteristics,epidemiological and disease characteristics,detection methods,research progress of Tyzzer's organism,as well as the prevention and treatment of Tyzzer's organism.
作者
陶俊豪
鄢慧琼
谢珲
应华忠
戴方伟
TAO Junhao;YAN Huiqiong;XIE Hui;YING Huazhong;DAI Fangwei(Zhejiang Provincial Laboratory of Experimental Animal and Safety Evaluation Research,Laboratory Animal Center,Hangzhou Medical College,Hangzhou 310013,China)
出处
《实验动物与比较医学》
CAS
2022年第4期358-363,共6页
Laboratory Animal and Comparative Medicine
基金
浙江省医药卫生科技计划项目(2020KY530)“基于LAMP与dipstick集成的实验动物泰泽病原体病快速诊断新技术研究”。
关键词
泰泽病原体
泰泽氏病
研究进展
防治
Tyzzer organism
Tyzzer disease
Research progress
Prevention and treatment
