摘要
目的:研究高分辨率磁共振成像(HRMRI)在急性脑梗死(ACI)及短暂性脑缺血发作(TIA)患者症状性大脑中动脉(MCA)粥样硬化斑块特征观察中的价值。方法:选取医院收治的80例症状性MCA粥样硬化患者,依据弥散加权成像(DWI)检查结果将其分为ACI组(42例)和TIA组(38例)。两组均于治疗前行HRMRI检查,对比两组粥样硬化斑块分布情况,以及斑块表面不完整、斑块负荷百分比、斑块面积、血管面积(VA_(reference))、参考血管腔面积(LA_(reference))、血管最狭窄处面积(VA_(MLN))、血管最狭窄处管腔面积(LA_(MLN))、管壁面积(WA_(MLN))、狭窄率及重构方式的定量指标,通过受试者工作特征(ROC)曲线下面积(AUC)分析粥样硬化血管及斑块特征诊断的价值。结果:两组粥样硬化斑块分布情况以及VA_(reference)、LA_(reference)及VA_(MLN)对比均无统计学差异。ACI组斑块表面不完整患者占比显著高于TIA组,差异有统计学意义(x^(2)=8.717,P<0.05);斑块负荷百分比、斑块面积、WA_(MLN)及狭窄率显著高于TIA组,LA_(MLN)显著低于TIA组,差异有统计学意义(t=3.410,t=2.100,t=7.021,t=3.310,t=4.015;P<0.05)。经ROC曲线分析,斑块负荷百分比、斑块面积、LA_(MLN)、WA_(MLN)及狭窄率均能用于ACI的诊断,AUC分别为0.709、0.940、0.879、0.789和0.819。结论:症状性MCA粥样硬化中,ACI与TIA患者的斑块特征存在差异,HRMRI能够用于症状性MCA粥样硬化缺血性脑卒中发生风险的评估。
Objective:To investigate the value of high resolution magnetic resonance imaging(HRMRI) in the observation of atherosclerotic plaque characteristics of symptomatic middle cerebral artery(MCA) in patients with acute cerebral infarction(ACI) and transient ischemic attack(TIA).Methods:Eighty patients with symptomatic MCA atherosclerosis admitted to hospital were selected as the study subjects,and they were divided into ACI group(n=42) and TIA group(n=38) according to the results of diffusion weighted imaging(DWI) examination.Both groups underwent high resolution MRI before treatment,and the distribution of atherosclerotic plaque between two groups was compared.The quantitative indicators [incomplete plaque surface,load percentage of plaque,plaque area,vascular area(VA_(reference)),lumen area of reference(LA_(reference)),vessel area of stenosis(VA_(MLN)),lumen area of the vessel of stenosis(LA_(MLN)),wall area of vessel(WA_(MLN)),stenosis rate,reconstruction method] were also compared between the two groups.Finally,the area under curve(AUC) of receiver operating characteristics(ROC) curve was used to analyze the value of atherosclerotic vessels and plaque features in diagnosing ACI.Results:There were no significant differences in the distribution of atherosclerotic plaque,VA_(reference),and VA_(MLN) between two groups.And the proportion of patients with incomplete plaque surface in ACI group was significantly higher than that in TIA group(x^(2)=8.717,P<0.05),and the percentages of plaque load,plaque area,WA_(MLN) and stenosis rate in that were significantly higher than those in TIA group,and LA_(MLN) in that was significantly lower than that in TIA group,the differences of them between two groups were statistically significant(t=3.410,t=2.100,t=7.021,t=3.310,t=4.015,P<0.05).The results of ROC analysis showed that the percentages of plaque load,plaque area,LA_(MLN),WA_(MLN) and stenosis rate could all be used to diagnose ACI.The AUCs of them were 0.709,0.940,0.879,0.789 and 0.819,respectively.Conclusion:In symptomatic
作者
秦鑫
冯志慧
许海娜
王振平
钟健
余宁
QIN Xin;FENG Zhi-hui;XU Hai-na(Department of Radiology,Hainan General Hospital,Haikou 570311,China;不详)
出处
《中国医学装备》
2022年第8期57-61,共5页
China Medical Equipment
基金
海南省卫生健康科研项目(20A200224)“缺血性脑卒中及TIA患者大脑中动脉粥样硬化斑块的3.0T磁共振高分辨率研究”。
