摘要
近年来,以粪菌移植(FMT)为代表的外源性微生物移植技术作为非标准化治疗方案被广泛用于治疗人类肠道疾病。基于不同动物上的研究表明,利用FMT干预或重建肠道菌群以解决与肠道微生物失调相关的畜禽生产、健康等问题是切实可行的。本文综述了当前国内外在猪上开展的FMT研究,分析比较了不同研究中FMT在重塑和改善肠道菌群的效果与差异之处,探讨了在猪上实施FMT需要注意的事项,以期为建立更标准、更安全的FMT技术体系及促进养猪生产上的FMT规范应用提供参考。
In recent years,exogenous microbial transplantation,represented by fecal microbiota transplantation(FMT),has been widely used as a non-standardized treatment for human intestinal diseases.Studies based on different animals indicate that it is feasible to use FMT for intestinal microbiota intervention or reconstruction to address production health problems related to intestinal microbiome disorders in livestock,poultry,and animals.In this paper,the current domestic and foreign FMT studies using pigs as receptors were reviewed,the effects and differences of FMT in reshaping and improving intestinal flora were analyzed and compared,and the matters to be paid attention to in the implementation of FMT were discussed,which aims to provide a reference for establishing a more standard and safer FMT technology system and promoting the application of FMT specification in the pig industry.
作者
张卓
蒋谦
刘作华
齐仁立
ZHANG Zhuo;JIANG Qian;LIU Zuohua;QI Renli(Chongqing Academy of Animal Science,Chongqing 402460,China;College of Animal Science and Technology,Hunan Agriculture University,Changsha 410000,China;Key Laboratory of Pig Industry Sciences,Ministry of Agriculture and Rural Affairs,Chongqing 402460,China)
出处
《动物营养学报》
CAS
CSCD
北大核心
2022年第8期4793-4801,共9页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
重庆市财政经费引导专项项目(21210,21515)
重庆市荣昌区农高专项项目(20206)
生猪产业技术体系岗位科学家项目。
关键词
粪菌移植
猪
标准化
应用
FMT
pigs
standardization
application
