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CD163在常见肿瘤中的临床意义及研究进展 被引量:6

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摘要 CD163属于清道夫受体家族,是人体血红蛋白触珠蛋白清除剂的亲和力受体,也是M2型肿瘤相关巨噬细胞表面特异性标志物。CD163是一种双重免疫调节剂,能够刺激免疫反应,又可以促进肿瘤细胞的增殖、侵袭及转移,在机体中发挥着重要的作用。目前,多项研究发现CD163对乳腺癌、肺癌、胃癌、胰腺癌、结直肠癌、肝癌等肿瘤的发生发展有很大的影响,这也深受很多学者的关注。本文就CD163的结构功能及在常见肿瘤中的研究进展及临床意义展开综述。
出处 《临床荟萃》 CAS 2022年第7期653-657,共5页 Clinical Focus
基金 国家自然科学基金资助项目——肿瘤相关巨噬细胞外泌体miRNA-221-3p调控HMGB1/NF-κB信号通路促进胃癌EMT的机制研究(82160588)。
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