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卡前列素氨丁三醇+改良B-Lynch术治疗顽固性宫缩乏力性产后出血的效果 被引量:2

Effect of carboprost tromethamine+modified B-Lynch surgery in the treatment of postpartum hemorrhage due to intractable uterine inertia
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摘要 目的 分析卡前列素氨丁三醇+改良B-Lynch术治疗顽固性宫缩乏力性产后出血的效果。方法 根据治疗方法的不同,将我院收治的48例顽固性宫缩乏力性产后出血产妇分为对照组(n=24,改良B-Lynch术)和试验组(n=24,卡前列素氨丁三醇+改良B-Lynch术)。比较两组的治疗效果。结果 试验组的治疗总有效率高于对照组(P<0.05)。试验组的产后2、24 h出血量少于对照组,子宫底下降速度大于对照组,产后开始泌乳时间、恶露持续时间短于对照组(P<0.05)。治疗后,试验组的血浆钙(Ca)水平高于对照组,D-二聚体、纤维蛋白原(FIB)、一氧化氮(NO)、一氧化氮合酶(NOS)水平低于对照组(P<0.05)。结论 卡前列素氨丁三醇+改良B-Lynch术治疗顽固性宫缩乏力性产后出血中的止血效果显著,利于促进产妇康复。 Objective To analyze the effect of carboprost tromethamine+modified B-Lynch surgery in the treatment of postpartum hemorrhage due to intractable uterine inertia.Methods According to different treatment methods,48 parturients with postpartum hemorrhage due to intractable uterine inertia admitted in our hospital were divided into control group(n=24,modified B-Lynch surgery)and experimental group(n=24,carboprost tromethamine+modified B-Lynch surgery).The treatment effects of the two groups were compared.Results The total effective rate of treatment in the experimental group was higher than that of the control group(P<0.05).The amount of bleeding at 2 and 24 h after delivery in the experimental group was less than that in the control group,the rate of uterine fundus decline was greater than that in the control group,and the time of postpartum lactation and duration of lochia were shorter than those in the control group(P<0.05).After treatment,the plasma calcium(Ca)level of the experimental group was higher than that of the control group,and the levels of D-dimer,fibrinogen(FIB),nitric oxide(NO)and nitric oxide syntllase(NOS)were lower than those in the control group(P<0.05).Conclusion Carboprost tromethamine+modified B-Lynch surgery in the treatment of postpartum hemorrhage due to intractable uterine inertia has a significant hemostatic effect,which is conducive to promote the rehabilitation of parturients.
作者 张慧琴 赵佳佳 ZHANG Huiqin;ZHAO Jiajia(Fugou County People's Hospital,Zhoukou 461300;Zhengzhou Central Hospital Affiliated to Zhengzhou University,Zhengzhou 450000,China)
出处 《临床医学研究与实践》 2022年第25期137-139,共3页 Clinical Research and Practice
关键词 产后出血 卡前列素氨丁三醇 改良B-Lynch术 postpartum hemorrhage carboprost tromethamine modified B-Lynch surgery
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