摘要
目的通过超声影像学检查分析利胆理气汤对慢性胆囊炎患者胆囊排空功能及胆汁超声影像学特点的影响结局。方法研究采用一次性横断面方法,并根据多阶段整群随机抽样法且在保证整体抽样准确性的前提下,最终抽取慢性胆囊炎患者86例作为观察对象。按照观察对象纳入先后次序,分别予以编号,采用随机数字表法按照1∶1比例进行随机分组,包括观察组和对照组各43例。对照组调整饮食、口服阿莫西林胶囊及熊去氧胆酸片;观察组在对照组基础上,服用利胆理气汤,连续12周。观察和比较纳入对象胆囊形态、胆囊壁厚度、胆囊排空功能及胆汁超声影像学特点。结果观察组痊愈率23.26%(10/43)、有效率41.86%(18/43)、总有效率95.35%(41/43)分别高于对照组的6.98%(3/43)、32.56%(14/43)、74.42%(32/43),无效率4.65%(2/43)低于对照组的25.58%(11/43)(P<0.05)。用药后较用药前,两组观察对象胆囊空腹容积、餐后不同时间点胆囊容积均先下降、后又升高,胆囊排空率先升高、后下降,胆汁透声良好构成比升高、胆汁透声差构成比下降(P<0.05);用药后,观察组胆囊空腹容积、餐后不同时间点胆囊容积均小于对照组,不同时间点胆囊排空率均高于对照组,胆汁透声良好构成比高于对照组、胆汁透声差构成比低于对照组(P<0.05)。结论超声影像学检查能有效显示利胆理气汤对慢性胆囊炎患者胆囊排空功能及胆汁状况具有明显的影响效应及作用价值,值得将利胆理气汤广泛应用于慢性胆囊患者中,达到养治结合、降低复发的目的。
Objective To analyze the effect of Lidan Liqi Decoction(利胆理气汤)on gallbladder emptying function and cho-lecystitis ultrasound imaging characteristics in patients with chronic cholecystitis.Methods A total of 86 patients with chronic cholecystitis were selected according to the one-time cross-sectional method and the multi-stage cluster random sampling method,on the premise of ensuring the overall sampling accuracy.According to the order of inclusion of the observed objects,they were numbered respectively.The random number table method was used to randomly divide them into groups according to a 1:1 ratio,including the observation group and the control group,with 43 cases in each group.In the control group,the diet was adjus-ted and Amoxicillin Capsule and Ursodeoxycholic Acid Tablet were taken orally.On the basis of the treatment in the control group,the observation group took Lidan Liqi Decoction,consecutively for 12 weeks.The gallbladder morphology,gallbladder wall thickness,gallbladder emptying function and the ultrasonographic characteristics of bile were observed and compared.Results The cure rate of the observation group was 23.26%(10/43),the effective rate was 41.86%(18/43)and the total effective rate was 95.35%(41/43),which were higher than those of the control group[6.98%(3/43),32.56%(32/43),74.42%(32/43)].The inefficiency was 4.65%(2/43)of the observation group,lower than that of the control group(25.58%,11/43)(P<0.05).Compared with those before,the fasting gallbladder volume and gallbladder volume at different postprandial time points in both groups were first decreased and then increased.The gallbladder empty rate was first increased and then decreased.The composi-tion ratio of good bile permeability was increased and the composition ratio of poor bile permeability decreased(P<0.05).After medication,the fasting gallbladder volume and gallbladder volume at different postprandial points in the observation group were lower than those in the control group.The gallbladder empty rates at different t
作者
宋会明
郑媛媛
鲁葆春
SONG Huiming;ZHENG Yuanyuan;LU Baochun(Shaoxing People's Hospital,Zhejiang University,Shaoxing 312000,Zhejiang,China)
出处
《中华中医药学刊》
CAS
北大核心
2022年第6期185-188,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家中医药管理局中医药行业科研项目(2019082068)
浙江省卫生健康委员会面上项目(2021KY372)。
关键词
超声
慢性胆囊炎
利胆理气汤
胆囊
胆汁
ultrasound
chronic cholecystitis
Libile Liqi Decoction(利胆理气汤)
gallbladder
bile