摘要
类风湿性关节炎(Rheumatoid arthritis,RA)是一种比较难治愈的慢性全身性免疫疾病。其主要表现为关节滑膜炎及浆膜、眼、皮肤、心肺、血管等结缔组织广泛性炎症。如何有效地治疗和预防类风湿性关节炎的发生和发展及提高RA患者的生活质量已经成为医学领域中亟待解决的难题。民族药中广泛存在具有抗类风湿性关节炎作用的药物,从细胞因子、信号通路、肠道菌群等方面对民族药抗类风湿性关节炎的作用机制进行文献综述,以期为该病的实验研究及临床应用提供更多的参考。
Rheumatoid arthritis(RA)is a chronic systemic immune disease that is difficult to cure.Its main manifestations are synovitis and extensive inflammation of connective tissue such as serosa,eyes,skin,heart,lung and blood vessels.How to effectively treat and prevent the occurrence and development of RA and improve the quality of life of RA patients has become an urgent problem to be solved in the medical field.There are many drugs with anti RA effect in national medicine.This paper re-viewed the literature on the mechanism of the anti RA effect of national medicine from the aspects of cytokines,signal pathway and intestinal flora,in order to provide more references for the experimental research and clinical application of the disease.
作者
叶梅芳
刘媛媛
丘琴
蒙雪雁
江露娟
史俊豪
YE Meifang;LIU Yuanyuan;QIU Qin;MENG Xueyan;JIANG Lujuan;SHI Junhao(Guangxi University of Chinese Medicine,Nanning 530200,Guangxi,China;Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development,Nanning 530200,Guangxi,China)
出处
《中华中医药学刊》
CAS
北大核心
2022年第6期55-60,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金(82060713)
中药学广西一流学科(桂教科研〔2018〕12号)
广西科技基地和人才专项(桂科AD20238058)
广西壮瑶药重点实验室项目(桂科基字〔2014〕32号)
广西“2011协同创新中心”-壮瑶药协同创新中心项目(桂教科研〔2013〕20号)
广西一流学科-中药学(0501802815)
广西重点学科(壮药学)项目(桂教科研〔2013〕16号)。
关键词
民族药
抗类风湿性关节炎
作用机制
national medicine
anti-rheumatoid arthritis
mechanism of action
