摘要
目的探讨针刺单穴内睛明治疗中重度干眼的疗效。方法将60例干眼患者随机分为针刺组和药物组。共治疗8周,随访32周。观察指标为Schirmer-I试验(SIT)值、泪膜破裂时间(TBUT)、角膜荧光素染色(CFS)、眼表疾病指数(OSDI)和针刺可接受性评价。结果治疗8周后,SIT值针刺组明显高于药物组(P<0.05)。OSDI评分在8周和随访时组间有显著差异。泪膜破裂时间和角膜荧光素染色的变化在8周时没有显著差异,其中5例出现针刺相关不良事件。结论针刺单穴内睛明能显著促进泪液分泌,改善多种眼部不适症状。针灸对中重度干眼的疗效优于人工泪液。
Objective To investigate the curative effect of acupuncture at a single point Neijingming in the treatment of moderate to severe dry eye disease(DED).Methods A total of sixty DED patients were randomly divided into an acupuncture group and an artificial tears(AT)group.Either acupuncture or AT was performed for an 8-week period,and a 32-week follow-up was performed.The outcome measures included the Schirmer-I test(SIT)value,the tear-film break-up time(TBUT),corneal fluorescein staining(CFS),the ocular surface disease index(OSDI),and the acupuncture acceptability.Adverse events were also monitored and documented.Results After 8 weeks of treatment,there was a significant difference in the SIT values between the acupuncture group and the artificial tears group(P<0.05).There was a significant difference in the OSDI scores between the two groups at the 8th week and the follow-up,while the changes in the tear film break-up time and corneal fluorescein staining were not significantly different at the 8th week,and five cases experienced acupuncture-related adverse events.Conclusion Acupuncture at a single point Neijingming can significantly promote tear secretion and improve multiple eye discomfort symptoms,which is more effective than artificial tears for moderate to severe dry eye disease.
作者
张雪
石欢
马菊梅
谷秀丽
朱文增
ZHANG Xue;SHI Huan;MA Jumei;GU Xiuli;ZHU Wenzeng(South Area of Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 102618,China;Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《吉林中医药》
2022年第7期834-837,共4页
Jilin Journal of Chinese Medicine
基金
北京市中医药科技发展资金规划项目(JJ2018-57)
中国中医科学院广安门医院南区所级课题(Y2018-11)。
