摘要
血管内膜增生是多种血管增生性疾病的基本病理生理特征,而慢性应激可导致血管内膜增生。近年来,慢性应激对于血管内膜增生的作用及通过组织蛋白酶S、组织蛋白酶K相关信号通路引起血管内膜增生的研究日趋增多,两者之间关系越来越受到关注。该文就慢性应激在血管内膜增生中的作用及分子机制的研究进展作一综述。
Vascular intimal hyperplasia is the basic pathophysiological feature of a variety of vascular proliferative diseases,and chronic stress may lead to vascular intimal hyperplasia.In recent years,the role of chronic stress in vascular intimal hyperplasia and the studies of vascular intimal hyperplasia caused by cathepsin S(CatS)and cathepsin K(CatK)related signaling pathways have been increasing,and the relationship between chronic stress and vascular intimal hyperplasia has attracted more and more attention.This paper reviews the research progress on the role of chronic stress in vascular intimal hyperplasia and its molecular mechanism.
作者
王铮(综述)
李香(审校)
WANG Zheng;LI Xiang(Department of Cardiovascular Medicine,Yanbian University Hospital,Jilin 133000,China)
出处
《中国临床新医学》
2022年第7期658-661,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
国家自然科学基金资助项目(编号:82060052)。
