摘要
目的:观察清热行气消胀法治疗肝郁化火型慢性胰腺炎的临床疗效。方法:将86例慢性胰腺炎患者按随机数字表法分为对照组与观察组各43例。对照组给予对症治疗,观察组在对照组基础上给予清热行气消胀法治疗。比较2组临床疗效及治疗前后中医证候积分、胰腺功能指标及炎症因子指标。结果:观察组临床总有效率93.02%,高于对照组74.42%(P<0.05)。治疗后,2组口苦口干、嗳腐吞酸、烦躁易怒、两胁窜痛、脘腹胀满、大便秘结症状积分以及总积分均低于治疗前(P<0.05),且观察组中医证候积分低于对照组(P<0.05)。治疗后,2组空腹血糖、甘油三酯、脂肪酶、淀粉酶、尿淀粉酶水平均低于治疗前(P<0.05),且观察组降低幅度大于对照组(P<0.05)。治疗后,2组C-反应蛋白、白细胞介素(IL)-6、IL-8水平均低于治疗前(P<0.05),且观察组治疗后炎症因子水平低于对照组(P<0.05)。结论:清热行气消胀法可改善肝郁化火型慢性胰腺炎患者胰腺功能,降低炎症反应,提高临床疗效。
Objective:To observe the clinical effect of Qingre Xingqi Xiaozhang method for chronic pancreatitis of liver constraint transforming into fire type.Methods:A total of 86 cases of patients with chronic pancreatitis were divided into the control group and the observation group according to the random number table method,with 43 cases in each group.The control group was treated with symptomatic treatment,and the observation group was additionally treated with Qingre Xingqi Xiaozhang method based on the treatment of the control group.Chinese medicine syndrome scores,pancreatic function indexes and inflammatory factors before and after treatment,as well as clinical effects were compared between the two groups.Results:The total effective rate was 93.02%in the observation group,higher than that of 74.42%in the control group(P<0.05).After treatment,symptom scores of bitter taste in the mouth and dry mouth,eructation with fetid odor and acid swallowing,vexation,agitation and irascibility,scurrying pain in both sides of the chest,abdominal fullness and distention,constipation,and reddish urine as well as the total scores in the two groups were lower those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the levels of fasting blood glucose,triglyceride,lipase,amylase and urinary amylase in the two groups were lower than those before treatment(P<0.05),and the decrease range in the observation group was greater than that in the control group(P<0.05).After treatment,the levels of C-reactive protein,interleukin(IL)-6 and IL-8 in the two groups were lower than those before treatment(P<0.05),and the levels of inflammatory factors in the observation group were lower than those in the control group(P<0.05).Conclusion:For patients with chronic pancreatitis of liver constraint transforming into fire type,Qingre Xingqi Xiaozhang method can improve their pancreatic function,reduce inflammatory responses,and improve clinical effects.
作者
高新建
杜璞
赵秋升
GAO Xinjian;DU Pu;ZHAO Qiusheng
出处
《新中医》
CAS
2022年第13期55-59,共5页
New Chinese Medicine
关键词
慢性胰腺炎
肝郁化火型
清热行气消胀法
C-反应蛋白
白细胞介素-6
Chronic pancreatitis
Liver constraint transforming into fire type
Qingre Xingqi Xiaozhang method
C-reactive protein
Interleukin-6
