摘要
目的:观察夏附逐痰汤联合克林澳治疗脑梗死的临床效果。方法:选取120例脑梗死患者,根据不同治疗方案将其分为对照组与观察组各60例。对照组应用克林澳治疗,观察组应用克林澳联合夏附逐痰汤治疗。治疗2周后,比较2组临床疗效、神经功能评分(NIHSS)、运动功能评分(Fugl-Meyer)、日常生活活动能力评分(Barthel),炎症因子[白细胞介素-6(IL-6)、超敏C-反应蛋白(hs-CRP)]水平。结果:观察组总有效率为91.67%,对照组为76.67%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组NIHSS评分比较,差异无统计学意义(P>0.05);治疗后,观察组NIHSS评分低于对照组(P<0.05)。治疗前,2组Fugl-Meyer、Barthel评分比较,差异无统计学意义(P>0.05);治疗后,观察组Fugl-Meyer、Barthel评分均高于对照组(P<0.05)。治疗前,2组IL-6、hs-CRP水平比较,差异无统计学意义(P>0.05);治疗后,观察组IL-6、hs-CRP水平均低于对照组(P<0.05)。结论:夏附逐痰汤联合克林澳治疗脑梗死患者临床效果确切,能抑制机体炎症反应,减轻患者神经功能缺损程度,提高其运动功能及日常生活活动能力。
Objective:To observe the clinical effect of Xiafu Zhutan tang combined with cinepazide maleate injection for cerebral embolism.Methods:A total of 120 cases of patients with cerebral embolism were selected and divided into the control group and the observation group according to different treatment plans,with 60 cases in each group.The control group was treated with cinepazide maleate injection,and the observation group was treated with cinepazide maleate injection combined with Xiafu Zhutan tang.After two weeks of treatment,the clinical effects,the scores of National Institutes of Health Stroke Scale(NIHSS),Fugl-Meyer Motor Assessment(Fugl-Meyer)and Barthel Index for Activities of Daily Living(Barthel),and the levels of inflammatory factors including interleukin-6(IL-6)and hypersensitive C-reactive protein(hs-CRP)in the two groups were compared.Results:The total effective rate was 91.67%in the observation group and 76.67%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of NIHSS scores between the two groups(P>0.05).After treatment,NIHSS score in the observation group was lower than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the scores of Fugl-Meyer and Barthel between the two groups(P>0.05).After treatment,the scores of FuglMeyer and Barthel in the observation group were higher than those in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the levels of IL-6 and hs-CRP between the two groups(P>0.05).After treatment,the levels of IL-6 and hs-CRP in the observation group were lower than those in the control group(P<0.05).Conclusion:The therapy of Xiafu Zhutan tang combined with cinepazide maleate injection for patients with cerebral embolism has a definite clinical effect,which can inhibit the inflammatory response,significantly reduce the degree of neurological impairment,and improv
作者
黄静文
李游
HUANG Jingwen;LI You
出处
《新中医》
CAS
2022年第12期77-80,共4页
New Chinese Medicine
关键词
脑梗死
夏附逐痰汤
克林澳
神经功能
运动功能
日常生活活动能力
炎症因子
Cerebral embolism
Xiafu Zhutan tang
Cinepazide maleate injection
Neurological function
Motor function
Activities of daily living
Inflammatory factors
