摘要
目的分析不同结构的取栓支架的机械性能,为取栓支架的设计以及临床选择提供理论支持。方法通过有限元分析以及体外模拟实验对3款不同结构的取栓支架(B3、K4、X)进行评估,分析指标是径向支撑力、回撤力以及模拟取栓过程中的血栓状态。结果实验得到B3、K4、X取栓支架的径向支撑力分别为0.48、0.43、0.51 N,且压握尺寸越大,取栓支架的径向支撑力越大;当压握尺寸大于3 mm时,支架的径向支撑力显著增大。模拟取栓实验结果表明,B3、K4、X支架的回撤力峰值分别为0.410、0.451、0.501 N,实验结果与有限元分析的结果具有趋势一致性。结论实验结果与有限元结果均表明,X支架具有更好的力学性能。此方法可作为评估取栓支架性能的一种分析方法,为取栓支架的性能提高和研发提供参考。
Objective To analyze mechanical properties of stent retrievers with different structures,and provide theoretical support for the design and clinical selection of stent retrievers.Methods Three kinds of stent retrievers with different structures(B3,K4,X)were evaluated by finite element analysis and in vitro simulation experiment.The analytic parameters were radial support force,withdrawal force and thrombosis state during the thrombotomy test.Results The radial support forces of B3,K4,X stent retrievers obtained from the experiment were 0.48 N,0.43 N,0.51 N,respectively.The larger the crimping distance,the greater the radial support force of stent retrievers.The radial support force of the stent increased significantly when the crimping distance was larger than 3 mm.The simulated thrombus removal experiment results showed that the peak withdrawal forces of B3,K4,X stent retrievers were 0.410 N,0.451 N,0.501 N,respectively.The experimental results were consistent with the finite element analysis results.Conclusions Both the experimental results and the finite element results showed that the X stent has better mechanical properties.This method can be used as an analytic method to evaluate performance of the stent retrievers,and provide references for performance improvement and development of the stent retrievers.
作者
邱晓键
张晓颖
谷雪莲
肖有申
赵宇轩
QIU Xiaojian;ZHANG Xiaoying;GU Xuelian;XIAO Youshen;ZHAO Yuxuan(School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2022年第3期419-424,共6页
Journal of Medical Biomechanics
基金
上海市生物医学工程研究生示范实践基地(1017308011)。
关键词
取栓支架
体外模拟
取栓实验
回撤力
径向支撑力
stent retriever
in vitro simulation
thrombectomy test
withdrawal force
radial support force
