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阻塞性睡眠呼吸暂停综合征相关性高血压的机制和治疗研究进展

Treatment Prospect of obstructive sleep apnea syndrome-related Hypertension
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摘要 阻塞性睡眠呼吸暂停综合征(OSAHS)是一种睡眠呼吸疾病。OSAHS患者会出现低氧血症、氧化应激等情况,继而引发相关激素变化、自主神经调节紊乱、内皮功能障碍等,最终导致以OSAHS相关高血压为代表的心血管疾病发生。然而目前OSAHS相关性高血压的病理生理机制尚未明确,本文就OSAHS相关性高血压的研究进展进行综述,以期为OSAHS的诊断及治疗提供帮助。 Obstructive sleep apnea syndrome(OSAHS)is a type of sleep breathing disease that triggers changes in related hormones,autonomic nervous regulation disorders,and endothelial dysfunction through a series of mechanisms such as hypoxemia and oxidative stress,which ultimately lead to OSAHS-related Cardiovascular diseases represented by hypertension occur.At present,the pathophysiological mechanism of OSAHS-related hypertension is not fully understood.Understanding the research progress of OSAHS-related hypertension can help for the diagnosis and treatment of the disease.
作者 陈策 李果明 CHEN Ce;LI Guoming(Department of Cardiology,The First Clinical Medical College,Guangdong Medical University,zhanjiang,Guangdong 524000,China;Department of Cardiology,Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong 524000,China)
出处 《医药前沿》 2022年第18期28-30,共3页 Journal of Frontiers of Medicine
关键词 综述 高血压 阻塞性睡眠呼吸暂停综合征 间歇性缺氧 Review Hypertension Obstructive sleep apnea syndrome Intermittent hypoxia
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