摘要
目的探讨全凭静脉麻醉对腹腔镜下全子宫切除术患者术后恢复及疼痛程度的影响。方法选择2017年1月至2020年12月我院收治的400例行腹腔镜下全子宫切除术患者作为研究对象,根据麻醉方式的不同将其分为对照组(200例,静吸复合麻醉)和试验组(200例,全凭静脉麻醉)。比较两组的术后恢复指标、认知功能、炎症因子、凝血功能指标及疼痛程度。结果试验组的术后睁眼时间、呼吸恢复时间、拔出气管插管时间、术后肠道功能恢复时间及住院时间均短于对照组,差异具有统计学意义(P<0.05)。术前,两组的简易智力状态检查量表(MMSE)评分、肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)水平比较,差异无统计学意义(P>0.05);术后3、6 h,试验组的MMSE评分高于对照组,TNF-α、IL-6水平低于对照组,差异具有统计学意义(P<0.05)。术前,两组的凝血酶原时间(PT)、血小板计数(PLT)、纤维蛋白原(FIB)水平比较,差异无统计学意义(P>0.05);术后6 h,两组的PT、PLT均减小,FIB水平均升高,但试验组优于对照组,差异具有统计学意义(P<0.05)。术后1、2、4 h,试验组的视觉模拟评分法(VAS)评分低于对照组,差异具有统计学意义(P<0.05)。结论全凭静脉麻醉应用于腹腔镜下全子宫切除术中可取得理想的麻醉效果,促进患者术后恢复,有效减轻其术后疼痛程度,值得临床推广和应用。
Objective To explore the effects of total intravenous anesthesia on postoperative recovery and pain degree of patients undergoing laparoscopic total hysterectomy.Methods A total of 400 patients who underwent laparoscopic total hysterectomy admitted in our hospital from January 2017 to December 2020 were selected as the research objects,and the patients were divided into control group(200 cases,combined intravenous and inhalation anesthesia)and experimental group(200 cases,total intravenous anesthesia)according to different anesthesia methods.The postoperative recovery indexes,cognitive function,inflammatory factors,coagulation function indexes and pain degree were compared between the two groups.Results The postoperative eye opening time,respiratory recovery time,extubation time,postoperative intestinal function recovery time and hospitalization time in the experimental group were shorter than those in the control group,and the differences were statistically significant(P<0.05).Before operation,there were no significant differences in the mini-mental state examination(MMSE)score,tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)levels between the two groups(P>0.05);at 3 and 6 h after operation,the MMSE score in the experimental group was higher than that in the control group,and the levels of TNF-αand IL-6 were lower than those in the control group,the differences were statistically significant(P<0.05).Before operation,there were no significant differences in the prothrombin time(PT),platelet count(PLT)and fibrinogen(FIB)level between the two groups(P>0.05);at 6 h after operation,PT and PLT in both groups decreased,and FIB level in both groups increased,but those in the experimental group were better than the control group,the differences were statistically significant(P<0.05).At 1,2,and 4 h after operation,the visual analogue scale(VAS)score in the experimental group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The total intravenous anesthesia
作者
王夏
刘轩
WANG Xia;LIU Xuan(Baoji Second People's Hospital,Baoji 721002;Affiliated Baoji Hospital of Xi'an Medical University,Baoji 721006,China)
出处
《临床医学研究与实践》
2022年第22期102-105,共4页
Clinical Research and Practice
关键词
腹腔镜
全子宫切除术
全凭静脉麻醉
术后恢复
疼痛程度
laparoscope
total hysterectomy
total intravenous anesthesia
postoperative recovery
pain degree
