摘要
目的:观察肠内营养不同递增输注速度对重症急性胰腺炎(SAP)患者喂养耐受性、生存质量和胃肠功能恢复的影响。方法:选取2019年3月~2021年2月期间我院收治的SAP患者120例,按照随机数字表法分为低速组、中速组和高速组,各为40例,输注速度递增幅度由低到高给予肠内营养。对比三组患者的腹内压、喂养耐受性、生存质量和胃肠功能恢复情况。结果:干预8 h后、干预16 h后、干预20 h后低速组腹内压低于高速组、中速组,而中速组低于高速组(P<0.05)。低速组排气排便恢复时间、肠鸣音恢复时间、经口进食时间、腹胀缓解时间短于中速组、高速组,中速组则短于高速组(P<0.05)。低速组干预7 d后世界卫生组织生存质量简明量表(WHO-QOL-BREF)各维度评分高于中速组、高速组,中速组则高于高速组(P<0.05)。低速组喂养不耐受发生率低于中速组、高速组,中速组则低于高速组(P<0.05)。结论:肠内营养低速递增输注有利于防止腹内压升高,提高SAP患者喂养耐受性,促进胃肠功能恢复,进而提高患者生存质量。
Objective:To observe the effects of different incremental infusion speed of enteral nutrition on feeding tolerance,quality of life and gastrointestinal function recovery in patients with severe acute pancreatitis(SAP).Methods:120 patients with SAP who were treated in our hospital from March 2019 to February 2021 were selected,and they were randomly divided into low-speed group,medium-speed group and high-speed group,with 40 cases in each group,the increasing range of infusion rate was from low to high,and enteral nutrition was given.The intra-abdominal pressure,feeding tolerance,quality of life and gastrointestinal function recovery of the three groups were compared.Results:8 h after intervention,16 h after intervention and 20 h after intervention,the intra-abdominal pressure in low-speed group was lower than that in high-speed group and medium-speed group,while that in medium-speed group was lower than that in high-speed group(P<0.05).The exhaust and defecation recovery time,bowel sound recovery time,oral feeding time and abdominal distension relief time in low-speed group were shorter than those in medium-speed group and high-speed group,while those in medium-speed group were shorter than those in high-speed group(P<0.05).7 d after intervention,the scores of all dimensions of the world health organization the quality of life-BREF(WHO-QOL-BREF)in the low-speed group were higher than those in the medium-speed group and the high-speed group,while those in the medium-speed group were higher than those in the high-speed group(P<0.05).The incidence of feeding intolerance in low-speed group was lower than that in medium-speed group and high-speed group,and that in medium-speed group was lower than that in high-speed group(P<0.05).Conclusion:The low-speed incremental infusion of enteral nutrition is helpful to prevent the increase of intra-abdominal pressure,improve the feeding tolerance of patients with SAP,promote the gastrointestinal function recovery,and then improve the quality of life of patients.
作者
鹿振辉
刘娜
石颖
赵海颖
董艳
LUZhen-hui;LIU Na;SHI Ying;ZHAO Hai-ying;DONG Yan(Department of Critical Medicine,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing,100730,China;General Surgery,Beijing Tongrcn Hospital Affiliated to Capital Medical University,Beijing,100730,China)
出处
《现代生物医学进展》
CAS
2022年第10期1846-1850,共5页
Progress in Modern Biomedicine
基金
北京市医院管理局"青苗"计划项目(QML20180206)。
关键词
肠内营养
输注速度
重症急性胰腺炎
喂养耐受性
生存质量
胃肠功能
Enteral nutrition
Infusion speed
Severe acute pancreatitis
Feeding tolerance
Quality of life
Gastrointestinal function
