摘要
Dear Editor,The persistent presence of ground-glass opacity nodules(GGN)on thin-section computed tomography(CT)usually suggests the presence of lung adenocarcinoma,1 which include atypical adenomatous hyperplasia(AAH),adenocarcinoma in situ(AIS),minimally invasive adenocarcinoma,and invasive adenocarcinoma(AD).2 Recent data indicate that up to 20%of GGN patients(3%of the screening population)are diagnosed with synchronous multiple ground-glass nodules(SM-GGNs).3 At present,neither auxiliary tests that could assist in differential diagnosis nor recommended strategy for the identification and treatment of GGNs exist in the clinical practice guidelines for lung cancer,although clinical evidence suggests that SM-GGNs are more complicated,making treatment decisions difficult.
基金
funded by the projects from the National Natural Science Foundation of China(91959126)
Shanghai Hospital Development Center(SHDC12017114)
Shanghai Pulmonary Hospital Innovation Team(FKCX1906,FKXY1902,FKLY2007,FK1943)
Shanghai Science and Technology Committee(20YF1441100,20XD1403000,18DZ2293400).
