摘要
目的探讨分析在经导管肝动脉化疗栓塞术中运用载药微球的护理配合及效果。方法将2020年1月-2020年12月我院收治的45例行载药微球经导管肝动脉化疗栓塞术治疗+精准护理的肝癌患者列为观察组,另外筛选此前我院2019年1月-2019年12月未实施载药微球与精准护理的45例患者列为对照组,比较两组患者的临床治疗效果,干预前后的生活质量、炎症反应、心理状态及护理满意度。结果观察组患者的临床治疗总有效率为60.00%显著高于对照组患者的临床治疗总有效率42.22%,组间比较差异具有统计学意义(P<0.05);在护理干预前,两组患者的生活质量并无显著差异(P>0.05);在护理干预后,观察组患者的WHOQOL-100生存质量量表各维度值均高于对照组,组间比较有较大差别(P<0.05);观察组患者护理前后的焦虑、抑郁改善程度显著优于对照组,组间比较有较大差别(P<0.05);观察组的各项并发症发生率均低于对照组,其中贫血/营养不良,转氨酶升高、周围神经毒性、中性线粒细胞减少、尿素氮升高以及感染均存在明显差异,组间比较差异具有统计学意义(P<0.05)。结论在经导管肝动脉化疗栓塞术中运用载药微球可以显著提高手术疗效,值得临床推广,患者在术后仍然存在一定不良反应,在治疗过程中对患者针对性实施相应的护理干预,能够改善患者的生活质量,提高再次治疗的依从性。
Objective To explore and analyze the nursing cooperation and effect of drug loaded microspheres in transcatheter hepatic artery chemoembolization.Methods 45 patients with liver cancer treated by drug loaded microspheres transcatheter hepatic artery chemoembolization+precision care in our hospital from January 2019 to December 2020 were listed as the observation group.In addition,45 patients who had not implemented drug loaded microspheres and precision care in our hospital were selected as the control group.The clinical treatment effects,quality of life,inflammatory response,and Psychological status and nursing satisfaction.Results The total effective rate of clinical treatment in the observation group was 60.00%,which was significantly higher than 42.22%in the control group(P<0.05);Before nursing intervention,there was no significant difference in quality of life between the two groups(P>0.05);After nursing intervention,the dimensions of WHOQOL-100 quality of life scale in the observation group were higher than those in the control group(P<0.05);The improvement of anxiety and depression in the observation group before and after nursing was significantly better than that in the control group(P<0.05);The incidence of complications in the observation group was lower than that in the control group.There were significant differences in anemia/malnutrition,elevated aminotransferase,peripheral neurotoxicity,neutropenia,elevated urea nitrogen and infection between the groups(P<0.05).Conclusion The use of drug loaded microspheres in transcatheter hepatic artery chemoembolization can significantly improve the surgical efficacy,which is worthy of clinical promotion.Patients still have some adverse reactions after operation.The targeted implementation of corresponding nursing intervention in the treatment process can improve the quality of life of patients and improve the compliance of re treatment.
作者
马强
MA Qiang(Zhongshan People’s Hospital,Zhongshan,Guangdong 528403)
出处
《智慧健康》
2022年第8期151-155,共5页
Smart Healthcare
关键词
经导管肝动脉化疗栓塞术
载药微球
护理配合
肝癌
Transcatheter hepatic arterial chemoembolization
Drug loaded microspheres
Nursing cooperation
Liver cancer
