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舒芬太尼复合罗哌卡因应用于硬膜外分娩镇痛的适宜输注模式探讨

Study on the Suitable Infusion Mode of Sufentanil Combined with Ropivacaine for Epidural Labor Analgesia
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摘要 目的 本研究使用舒芬太尼复合罗哌卡因进行硬膜外分娩镇痛,旨在探讨PIEB和CEI两种输注模式何种更适宜分娩镇痛。方法 选择2019年10月-2021年10月在我院行硬膜外分娩镇痛产妇100例,随机分为组和C组,每组50例。两组产妇均接受硬膜外分娩镇痛,均使用相同配方镇痛泵。组镇痛泵为PIEB模式,C组为CEI模式。记录两组产妇镇痛前、镇痛后10min、镇痛后30min、宫口开全时疼痛VAS评分、运动神经阻滞Bromage评分、胎心率;记录两组胎儿娩出后1min Apgar评分及5min Apgar评分;记录两组产妇镇痛药物使用总量、按压PCEA次数和PCEA有效按压次数;记录两组产妇分娩镇痛期间不良反应发生情况。结果 与C组比较,组产妇镇痛后10min、镇痛后30min、宫口开全时疼痛VAS评分明显降低(P <0.05),其余时间点两组产妇疼痛VAS评分比较差异无统计学意义(P>0.05);两组产妇不同时间点运动神经阻滞评分、胎心率比较差异无统计学意义(P>0.05),组产妇镇痛药物使用总量、按压PCEA次数和PCEA有效按压次数明显减少(P <0.05)。结论 程控硬膜外间歇脉冲输注模式较连续输注更适合硬膜外分娩镇痛,镇痛效果更佳,镇痛药物用量更少。 Objective This study used sufentanil combined with ropivacaine for epidural labor analgesia, in order to explore which of the two infusion modes of PIEB and CEI is more suitable for labor analgesia. Methods 100 pregnant women who underwent epidural labor analgesia in our hospital from October 2019 to October 2021 were randomly divided into group P and group C, with 50 cases in each group. Both groups received epidural labor analgesia and used the same formula analgesic pump. The analgesic pump in group P was PIEB mode and group C was CEI mode. VAS score of pain, Bromage score of motor nerve block and fetal heart rate were recorded before analgesia, 10 min after analgesia, 30 min after analgesia, and the whole time of uterine opening.Apgar score at 1 min and Apgar score at 5 min after delivery were recorded.The total amount of analgesic drugs used, the number of PCEA compressions and the number of effective PCEA compressions were recorded in the two groups. Adverse reactions during labor analgesia were recorded in the two groups. Results Compared with group C, the VAS scores of maternal pain in group P decreased significantly at 10 min,30 min and the whole time of uterine opening(P <0.05). There was no significant difference between the two groups at other time points(P >0.05);There was no significant difference in motor nerve block score and fetal heart rate between the two groups at different time points(P >0.05). The total use of analgesic drugs, the times of pressing PCEA and the times of effective pressing PCEA decreased significantly in group P(P < 0.05).Conclusion The programmed epidural intermittent pulse infusion mode is more suitable for epidural labor analgesia than continuous infusion. The analgesic effect is better and the dosage of analgesic drugs is less.
作者 张雁翔 夏景鸿 何彬彬 ZHANG Yanxiang;XIA Jinghong;HE Binbin(Maternal and Child Health and Family Planning Service Center of Rongcheng District,Jieyang,Guangdong 522000)
出处 《智慧健康》 2022年第11期127-129,133,共4页 Smart Healthcare
关键词 舒芬太尼 罗哌卡因 分娩镇痛 输注模式 Sufentanil Ropivacaine Labor analgesia Infusion mode
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