摘要
局灶性皮质发育不良(focal cortical dysplasia,FCD)是导致药物难治性癫痫的常见原因之一,Ⅰ型在FCD中的占比为38.3%,而Ⅱ型占比为61.7%。手术是治疗FCD的有效方式。术前发现病灶并精准定位是决定手术方式及预后的重要因素。目前对于FCD的诊断主要依赖MRI检查,但是,高达40%的Ⅱ型FCD和85%的Ⅰ型FCD病灶在常规MRI上表现为阴性,给诊断和手术带来极大的难度。随着MRI硬件、软件及后处理技术的发展,极大提高了FCD在常规MRI表现为阴性的检出率(综合诊断增益率为31%),对病灶准确定位、指导手术、降低术后癫痫发作具有重要意义。因此本文就提高常规MRI表现为阴性的FCD检出率的方法进行综述。
Focal cortical dysplasia(FCD)is one of the common causes of drug refractory epilepsy.TypeⅠaccounts for 38.3%of the FCD lesions,while typeⅡaccounts for 61.7%.Surgery is an effective way for the treatment of FCD.Preoperative detection and accurate localization of the lesions are important factors affecting the mode of operation and prognosis.At present,the diagnosis of FCD mainly depends on MRI.However,up to 40%of typeⅡFCD and 85%of typeⅠFCD lesions are negative on conventional MRI,which brings great difficulty to diagnosis and operation.With the development of MRI hardware,software and post-processing technology,the negative detection rate of FCD in conventional MRI is greatly improved(overall diagnostic gain rate 31%).Which is great significance for accurate location of lesions,guiding surgery and reducing postoperative seizures.Therefore,this paper reviews the research progress of improving the detection methods of FCD negative on conventional MRI.
作者
俱京涛
陈楠
JU Jingtao;CHEN Nan(Department of Radiology and Nulear Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2022年第7期164-166,170,共4页
Chinese Journal of Magnetic Resonance Imaging
关键词
磁共振成像
局灶性皮质发育不良
脑磁图
癫痫
三维容积液体衰减反转恢复序列
双反转恢复序列
液体和白质抑制序列
三维边缘增强梯度回波序列
基于体素的形态学分析
形态学分析程序
基于表面形态学技术
卷积神经网络
magnetic resonance imaging
focal cortical dysplasia
magnetoencephalography
epilepsy
three-dimensional fluid attenuated inversion recover
double inversion recovery sequences
fluid and white matter suppression sequence
three-dimensional edge-enhancing gradient echo sequence
voxel-based morphometry
morphometric analysis program
surface-based morphometry
convolutional neural network
