摘要
目的探讨视网膜分支静脉阻塞(BRVO)病人的黄斑水肿(ME)情况以及与玻璃体积血(VH)的关系。方法回顾性研究。收集2018年1月至2021年12月首诊于安徽医科大学第二附属医院眼科新发的BRVO病人177例(177眼),根据是否合并VH分为单纯组(单纯BRVO)87眼和VH组(BRVO合并VH)90眼,分别对两组病人进行黄斑部光学相干断层扫描成像(OCT)检查(其中屈光间质严重混浊者行玻璃体切除手术后再行OCT检查),收集病人的最佳矫正视力(BCVA)、眼压(IOP)以及黄斑中心凹视网膜厚度(CMT)并进行统计学分析。结果VH组BCVA优于单纯组[(0.57±0.53)比(0.83±0.50),P=0.001],且CMT明显低于单纯组[(233.38±37.97)μm比(586.06±112.27)μm,P<0.001],VH组眼压略高于单纯组[(15.63±2.33)mmHg比(14.28±1.63)mmHg,P<0.001],但两组病人眼压均在正常范围,BRVO病人CMT与VH之间存在显著的相关性,BRVO合并VH病人的ME明显减轻(B=−352.15,P<0.001)。结论BRVO合并VH病人的ME情况明显优于单纯BRVO,VH可能与BRVO病人ME的减轻呈统计学相关。
Objective To investigate the macular edema(ME)in patients with branch retinal vein occlusion(BRVO)and its relationship with vitreous hemorrhage(VH).Methods A retrospective study was conducted to collect data of a total of 177 eyes in 177 patients with naïve BRVO treated in the Ophthalmology Department of The Second Affiliated Hospital of Anhui Medical University from January 2018 to December 2021.According to whether they have VH or not,patients were assigned into simplex group(BRVO only,87 eyes)and VH group(BRVO complicated with VH,90 eyes).The macular optical coherence tomography(OCT)examination was performed on the two groups of patients respectively,among whom the patients with severe opacity in reactive stroma underwent OCT examination after vitrectomy.And data of the best corrected visual acuity(BCVA),intraocular pressure(IOP)and central macular thickness(CMT)of the patients were collected and analyzed statistically.Results Compared with the simplex group,the BCVA was better[(0.57±0.53)vs.(0.83±0.50),P=0.001],and the CMT was significantly thinner in the VH group[(233.38±37.97)μm vs.(586.06±112.27)μm,P<0.001].Although the intraocular pressure of the VH group was slightly higher than that of the simplex group[(15.63±2.33)mmHg vs.(14.28±1.63)mmHg,P<0.001],the intraocular pressures of both groups were within the normal range.There was a significant correlation between CMT and VH in patients with BRVO,and ME was significantly reduced in patients with BRVO complicated with VH(B=−352.15,P<0.001).Conclusion The macular edema in patients with BRVO complicated with VH is significantly better than that in patients with BRVO alone.VH may be closely related to the reduction of macular edema in patients with BRVO.
作者
刘东伟
蒋正轩
丁碧青
鲍宁
陶黎明
LIU Dongwei;JIANG Zhengxuan;DING Biqing;BAO Ning;TAO Liming(Department of Ophthalmology,The Second Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230601,China)
出处
《安徽医药》
CAS
2022年第8期1529-1532,共4页
Anhui Medical and Pharmaceutical Journal
基金
国家自然科学基金面上项目(82171043)
安徽医科大学校科研基金(2021xkj176)
安徽医科大学第二附属医院临床研究培育计划(2020LCYB19)。
