摘要
酒精性肝病与肠道微生物群落密切相关。酒精性肝病会导致肠道微生物群落失调,而微生物群落失调又可进一步加重肝病进程。本文综述了酒精性肝病与肠道微生物群落间的关系及作用机制,以及益生菌、益生元、合生元、后生元和噬菌体等肠道微生物及其相关产物改善或治疗肝病的研究前景。
Alcoholic liver diseases are closely related to gut microbiota.Alcoholic liver diseases can cause dysbiosis of gut microbiota that can affect the severity of liver disease progression.This review summarizes the research on the relationship and mechanism of gut microbiota and alcoholic liver diseases.Research of gut microbes,such as probiotics,prebiotics,synbiotics,postbiotics,and bacteriophages,and related products may improve or cure liver diseases.
作者
李国华
李鹤龄
陈智岗
刘海原
王宏
LI Guohua;LI Heling;CHEN Zhigang;LIU Haiyuan;WANG Hong(.State Key Laboratory of Primate Biomedical Research,Institute of Primate Translational Medicine,Kunming University of Science and Technology,Kunming 650500,China;Yunnan Key Laboratory of Primate Biomedical Research,Kunming 650500)
出处
《中国实验动物学报》
CAS
CSCD
北大核心
2022年第3期423-427,共5页
Acta Laboratorium Animalis Scientia Sinica
基金
国家自然科学基金项目(31960121)。
关键词
酒精性肝病
肠道微生物群落
研究进展
alcoholic liver diseases
gut microbiota
research progress
