摘要
目的应用压力-应变环(PSL)评价代谢综合征(MS)患者左室心肌做功的早期改变。方法选取2020年9月至2021年4月河北医科大学附属秦皇岛市第一医院就诊的尚未发生左室重构的MS患者70例作为MS组,同期选择65例健康志愿者作为对照组,进行心肌做功分析,包括整体做功指数(GWI)、整体做功效率(GWE)、整体有用功(GCW)、整体无用功(GWW),比较两组心肌做功参数的改变及与生化指标的相关性分析。结果MS组左室整体纵向应变(GLS)、GWI、GCW、GWE低于对照组,GWW高于对照组(均P<0.05)。Pearson相关分析表明,GWI与高密度脂蛋白胆固醇(HDL-C)呈正相关(r=0.194,P<0.05),与舒张压(DBP)、腰围(WC)、空腹血糖(Glu)、三酰甘油(TG)及GLS呈负相关(r=-0.257、-0.452、-0.239、-0.193、-0.758,均P<0.05);GWE与收缩压(SBP)、DBP、WC、Glu、TG及GLS呈负相关(r=-0.360、-0.269、-0.326、-0.352、-0.265、-0.663,均P<0.01),与HDL-C呈正相关(r=0.201,P<0.05);GCW与WC及GLS呈负相关(r=-0.299、-0.737,均P<0.001)。GWW与SBP、DBP、WC、Glu、TG及GLS呈正相关(r=0.435、0.308、0.413、0.547、0.272、0.400,均P<0.01),与HDL-C呈负相关(r=-0.336,P<0.001)。结论PSL可以定量评价MS患者的早期心肌做功改变且重复性良好,具有一定的潜在临床价值。
Objective To evaluate early left ventricular myocardial work in patients with metabolic syndrome(MS)by pressure-strain loops(PSL).Methods From September 2020 to April 2021,70 MS patients in the First Hospital of Qinhuangdao Affiliated to Hebei Medical University without left ventricular remodeling were selected as MS group and 65 normal controls as control group,PSL was used to obtain the myocardial power parameters,including global work index(GWI),global work efficiency(GWE),global constructive work(GCW)and global wasted work(GWW).The changes of the parameters were compared between the two groups and their correlations with biochemical parameters were performed in MS group.Results The left ventricular global longitudinal strain(GLS),GWI,GCW and GWE in MS group were lower than those in normal group,while GWW was higher than that in normal group(P<0.05).Pearson correlation analysis showed that GWI was positively correlated with high-density lipoprotein cholesterol(HDL-C)(r=0.194,P<0.05),and negatively correlated with diastolic blood pressure(DBP),waist circumference(WC),fasting blood glucose(Glu),triglyceride(TG)and GLS(r=-0.257,-0.452,-0.239,-0.193,-0.758,all P<0.05).GWE was negatively correlated with SBP,DBP,WC,Glu,TG and GLS(r=-0.360,-0.269,-0.326,-0.352,-0.265,-0.663,all P<0.01),and positively correlated with HDL-C(r=0.201,P<0.05).GCW was negatively correlated with WC and GLS(r=-0.299,-0.737;all P<0.001).GWW was positively correlated with SBP,DBP,WC,Glu,TG and GLS(r=0.435,0.308,0.413,0.547,0.272,0.400,all P<0.01),and negatively correlated with HDL-C(r=-0.336,P<0.001).Conclusions PSL can quantitatively evaluate the changes of early myocardial work in MS patients with good repeatability and has certain clinical value.
作者
孙立娟
肖丞炜
陈晓雪
王迪
薛坤
齐铮琴
Sun Lijuan;Xiao Chengwei;Chen Xiaoxue;Wang Di;Xue Kun;Qi Zhengqin(Department of Ultrasound Diagnosis,the First Hospital of Qinhuangdao,Hebei Medical University,Qinhuangdao 066000,China;Department of Ultrasound Medicine,Hebei Medical University,Shijiazhuang 050000,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2022年第5期414-419,共6页
Chinese Journal of Ultrasonography
关键词
超声检查
代谢综合征
心肌做功
心室功能
左
Ultrasonography
Metabolic syndrome
Myocardial work
Ventricular function,left
